Results 81 to 90 of about 1,326,939 (222)

Polymerase discordance in novel swine influenza H3N2v constellations is tolerated in swine but not human respiratory epithelial cells. [PDF]

PLoS ONE, 2014
Swine-origin H3N2v, a variant of H3N2 influenza virus, is a concern for novel reassortment with circulating pandemic H1N1 influenza virus (H1N1pdm09) in swine because this can lead to the emergence of a novel pandemic virus.
Joshua D Powell, Daniel Dlugolenski, Tamas Nagy, Jon Gabbard, Christopher Lee, Stephen M Tompkins, Ralph A Tripp   +6 more
doaj   +1 more source

Wildlife management in the United States – thoughts on evolving to better address species overabundance and disease transmission

Wildlife Society Bulletin, EarlyView.
Management options and actions are important for responsibly working to keep populations of sometimes overabundant species of invasive and native wildlife at levels that keep damage (e.g., agricultural, environmental, human health and safety) and disease (e.g., species specific, shared with livestock, zoonotic) associated with them at acceptable levels.
Kurt C. VerCauteren
wiley   +1 more source

Pseudotype-based neutralization assays for influenza: a systematic analysis [PDF]

, 2015
The use of vaccination against the influenza virus remains the most effective method of mitigating the significant morbidity and mortality caused by this virus.
Ferrara, Francesca, Keith eGrehan, Temperton, Nigel J., George William Carnell, Craig Peter Thompson, Francesca eFerrara, Nigel James Temperton, Grehan, Keith, Carnell, George W., Thompson, Craig P., Francesca Ferrara, Keith Grehan   +11 more
core   +1 more source

Swine as a Model for Influenza A Virus Infection and Immunity [PDF]

ILAR Journal, 2015
Influenza A viruses (IAVs) infect a variety of hosts, including humans, swine, and various avian species. The annual influenza disease burden in the human population remains significant even with current vaccine usage, and much about the pathogenesis and transmission of influenza viruses in humans remains unclear.
Daniela S, Rajao, Amy L, Vincent
openaire   +2 more sources

Computationally optimized broadly reactive vaccine based upon swine H1N1 influenza hemagglutinin sequences protects against both swine and human isolated viruses

Human Vaccines & Immunotherapeutics, 2019
Swine H1 influenza viruses were stable within pigs for nearly 70 years until in 1998 when a classical swine virus reassorted with avian and human influenza viruses to generate the novel triple reassortant H1N1 strain that eventually led to the 2009 ...
Amanda L. Skarlupka, Simon O. Owino, Lui P. Suzuki-Williams, Corey J. Crevar, Donald M. Carter, Ted M. Ross   +5 more
doaj   +1 more source

A live‐cell autophagy reporter reveals reversible vacuolation in naked mole‐rat skin fibroblasts under lysosomal stress

The FEBS Journal, EarlyView.
A tandem fluorescent mCherry–EGFP–LC3 reporter enables live‐cell visualisation of autophagy–lysosome dynamics in naked mole‐rat skin fibroblasts. Chloroquine‐induced lysosomal stress promotes accumulation of neutral LC3‐positive compartments and triggers pronounced LC3‐associated vacuolation.
Fangze Tong, Mateo P. Hoare, Laura J. Grundy, Filomena Gallo, Karin H. Müller, Ewan St. John Smith, Janet R. Kumita   +6 more
wiley   +1 more source

Influenza virus activation of the interferon system [PDF]

, 2015
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, E., Killip, M.J., Randall, R.E., Randall, R.E.; id_orcid   +3 more
core   +1 more source

Isolation and complete genomic characterization of H1N1 subtype swine influenza viruses in southern China through the 2009 pandemic

Virology Journal, 2011
Background The swine influenza (SI) is an infectious disease of swine and human. The novel swine-origin influenza A (H1N1) that emerged from April 2009 in Mexico spread rapidly and caused a human pandemic globally.
Xue Chunyi, Chen Feng, Chen Cuiying, Shang Huiqin, Wang Jing, Xie Qingmei, Ji Jun, Liu Yizhi, Cao Yongchang, Ma Jingyun, Bi Yingzuo   +10 more
doaj   +1 more source

TRANSMISSION OF SWINE INFLUENZA VIRUS BY LUNGWORM MIGRATION [PDF]

The Journal of Experimental Medicine, 1961
Experimental evidence is presented which confirms the reports by Shope (1, 2) that swine lungworms can serve as an intermediate host in transmitting swine influenza virus to pigs. The virus is present in a masked non-infective form as he showed and a provocative stimulus is necessary to initiate infection.
Sen, H.G., Kelley, G.W., Underahl, N.R., Young, G.A.   +3 more
openaire   +2 more sources

Influenza A Virus at the Exhibition Swine‐Human Interface in the USA

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction In the USA, zoonotic influenza A virus (IAV) transmission occurs frequently in youth who exhibit swine at agricultural competitions, presenting an ongoing pandemic risk. However, active surveillance in this high‐risk human population is lacking.
Dillon S. McBride, Martha I. Nelson, Hannah J. Cochran, Heather N. Nicholson, Elizabeth M. Ohl, Yunho Jang, Natosha Zanders, Dan Cui, Han Di, C. Todd Davis, John R. Barnes, Malania M. Wilson, Marie K. Kirby, Andrew S. Bowman, Jacqueline M. Nolting   +14 more
wiley   +1 more source