Results 121 to 130 of about 10,449 (207)

Pharmacokinetics Profile of Chitosan Nanoparticles in Chronic Lead-induced Toxicity Rats Model [PDF]

Chronic lead exposure induces ROS accumulation which causes physiological disorders. Chelation therapy has been widely used to overcome lead poisoning since it exerts only a few side effects. Nano chitosan prevents lead poisoning by inhibiting ROS.
Amalina, Nur Dina, Asmorowati, Dian Sri, Astari, Putri Dyah, Futri, Shafira Septiana, Marianti, Aditya, Mursiti, Sri, Negara, Legendra Gantar, Sholehah, Intan Kharyna, Sitompul, Faya Nuralda   +8 more
core   +2 more sources

Використання інструментів in silico для первинного скринінгу і прогнозу фармакологічної активності ряду нових похідних теофіліну

Annals of Mechnikov's Institute
Вступ. Фармакотерапія різноманітних захворювань потребує використання нових високоефективних лікарських засобів. На початкових етапах їх створення доцільно використовувати in silico методи скринінгу.
Liudmila Mosula, Serhii Yalovchuk, Viktoriia Mosula, Dmytro Korobko   +3 more
doaj   +1 more source

Evaluation of the Inhibitory Properties of Novel Compounds Against Acetylcholinesterase Using Computational Methods

Journal of Chemistry
Alzheimer’s disease (AD) is a neurodegenerative disorder mainly associated with the level of acetylcholine in the brain tissue cells. The extracellular β-amyloid protein accumulation in senile plaques is another reason for AD.
Mina Jamzad, Mehregan Fallah-Kalamsari, Mohsen Amini   +2 more
doaj   +1 more source

Three-Step Synthesis of N-(7-chloro-4-morpholinoquinolin-2-yl)benzamide from 4,7-Dichloroquinoline

Molbank
The quinoline derivative, N-(7-chloro-4-morpholinoquinolin-2-yl)benzamide, was synthesized in a conventional three-step procedure from 4,7-dichloroquinoline using a N-oxidation reaction/C2-amide formation reaction/C4 SNAr reaction sequence. The structure
Deiby F. Aparicio Acevedo, Marlyn C. Ortiz Villamizar, Vladimir V. Kouznetsov   +2 more
doaj   +1 more source

Synthesis, and characterization of magnesium oxide nanoparticles (MgO NPs) derived from Raphia hookeri seeds (RHS) and evaluation of their nano-pharmacokinetic properties

Discover Chemistry
The present study involves the development of MgO NPs from RHS and the evaluation of their nano-pharmacokinetic properties. The MgO NPs were synthesized via the solvothermal method using the aqueous extract of RHS.
Bamidele Honesty Akpeji, Vikash Singh
doaj   +1 more source

Synthesis of Anti-Schistosomal Heterocyclic Compounds Targeting Thioredoxin Glutathione Reductase [PDF]

chistosomiasis is a deadly and debilitating parasitic disease caused by Schistosoma mansoni which affects 200+ million people annually who come into contact with contaminated water.
Stewart, Alexander
core   +1 more source

Ligand-Based Pharmacophore Mapping and Virtual Screening for the Search of Biguanide-Like Molecules With Antidiabetic Potentials Targeting Liver Kinase B1. [PDF]

Biochem Res Int
Reza R, Samdani MN, Morshed N, Jebin RH, Ahmed I, Reza MS.   +5 more
europepmc   +1 more source

Correction: Comparative analysis of phytocompounds and repurposed drugs against dengue virus serotypes employing an in silico study. [PDF]

Sci Rep
Vats P, Rolta R, Salaria D, Sharma I, Verma A, Fadare OA, Verma M.   +6 more
europepmc   +1 more source

Differential Effects of Oleoyl Serine and HU-910 on Anxiety-like and Depression-like Behaviors in Male and Female WKY Rats. [PDF]

Int J Mol Sci
Gellman J, Zemliana N, Loterstein Y, Kachuki Dory E, Matas D, Shoval G, Sharon E, Koman I, Zalsman G, Koren L, Weller A, Kogan NM.   +11 more
europepmc   +1 more source

Green-Synthesized titanium dioxide Nanoparticle-Modified glass ionomer cement: in vitro and in Silico assessment of Mechanical, Physical, and safety properties performance. [PDF]

Sci Rep
Abozaid D, Ayad A, Ibrahim Y, Azab A, El-Aal MA, El-Safty S.   +5 more
europepmc   +1 more source