Results 1 to 10 of about 50,348 (248)
In memoriam - Konstantin Tsinman (1968 - 2020)
ADMET and DMPK, 2022 In memory of Konstantin Tsinman - Chief Scientific Officer at Pion Inc.,
Alex Avdeef
doaj +1 more source
ADME-AP: a database of ADME associated proteins [PDF]
Bioinformatics, 2002 Abstract Summary: Drug absorption, distribution, metabolism and excretion (ADME) often involve interaction of a drug with specific proteins. Knowledge about these ADME-associated proteins is important in facilitating the study of the molecular mechanism of disposition and individual response as well as therapeutic action of drugs.
Li Zhi Sun +4 more
openaire +2 more sources
Docking Simulations and Virtual Screening to find Novel Ligands for T3S in Yersinia pseudotuberculosis YPIII, A drug target for type III secretion (T3S) in the Gram-negative pathogen Yersinia pseudotuberculosis [PDF]
Chemical Review and Letters, 2021 In the Gram-negative pathogen Yersinia pseudotuberculosis and Chlamydia, the aggregate use of molecular docking, molecular dynamic simulations, and ADMET was successfully used to develop salicylidene acyl hydrazides as type III secretion (T3S) inhibitors.
Emmanuel Edache +3 more
doaj +1 more source
A middleware framework for constraint-based deployment and autonomic management of distributed applications [PDF]
, 2004 Submitted to Middleware 04 Funded by the EPSRC UK grant GR/S44501 "Secure LocationIndependent Autonomic Storage Architectures"We propose a middleware framework for deployment and subsequent autonomic management of component-based distributed applications.
Dearle, Alan +2 more
core +5 more sources
ADMET and DMPK, 2022 The stirring frequency exponent of -1/2 in the theoretical Levich expression appears to apply to PAMPA and Caco-2 assays, where efficient individual-well magnetic stirring ( > 20 RPM) is used.
Alex Avdeef
doaj +1 more source
ADMET and DMPK, 2023 Background and Purpose: The widely-used and practically insoluble diprotic acidic dye, bromothymol blue (BTB), is a neutral molecule in strongly acidic aqueous solutions.
Alex Avdeef
doaj +1 more source
Pharmacology Research & Perspectives, 2020 Ribociclib (LEE011, Kisqali ®) is a highly selective small molecule inhibitor of cyclin‐dependent kinases 4 and 6 (CDK4/6), which has been approved for the treatment of advanced or metastatic breast cancer.
Alexander D. James +8 more
doaj +1 more source
Uptake Transporters at the Blood–Brain Barrier and Their Role in Brain Drug Disposition
Pharmaceutics, 2023 Uptake drug transporters play a significant role in the pharmacokinetic of drugs within the brain, facilitating their entry into the central nervous system (CNS).
Md Masud Parvez +4 more
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ADM worldvolume geometry [PDF]
Nuclear Physics B - Proceedings Supplements, 2000 4 pages, Latex. Uses espcrc2.sty To appear in the proceedings of the Third Conference on Constrained Dynamics and Quantum Gravity, September, 1999. To appear in Nuclear Physics B (Proceedings Supplement)
Capovilla, Riccardo +2 more
openaire +3 more sources
Frontiers in Public Health, 2021 One of the most critical arenas for conflicts between parents and their children relates to food. Although parent-child conflicts about food are a real occurrence, this form of parent-child interaction has been rarely examined.
Ines Spielvogel +3 more
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