Results 11 to 20 of about 50,348 (248)
Flavones scaffold of Chromolaena odorata as a potential xanthine oxidase inhibitor: Induced Fit Docking and ADME studies [PDF]
BioImpacts, 2020 Introduction: Gout is a type of painful inflammation initiated by the interactions between monosodium urate crystals and connective tissue. Xanthine oxidase (XO) catalyzes the oxidation of hypoxanthine to xanthine, then to uric acid.
Babatomiwa Kikiowo +8 more
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, 2010 This chapter considers a complex of materials centred on the Alcestis of Euripides and its reception history as an opera (Lully, Gluck) in early modern France. The interest of this particular text is that its operatic setting by Lully generated a polemic
Wygant, A.
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Diversifying the chloroquinoline scaffold against SARS-COV-2 main protease: Virtual screening approach using cross-docking, sitemap analysis and molecular dynamics simulation [PDF]
Journal of the Serbian Chemical Society, 2023 The absence of designated remedies for coronavirus disease 19 (Covid-19) and the lack of treatment protocols drove scientists to propose new small molecules and to attempt to repurpose existing drugs against various targets of severe acute respiratory ...
Aissaoui Mohamed +4 more
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Cell Reports Medicine, 2021 Summary: Fibrosing chronic graft-versus-host disease (cGVHD) is a debilitating complication of allogeneic stem cell transplantation (alloSCT). A driver of fibrosis is the kynurenine (Kyn) pathway, and Kyn metabolism patterns and cytokines may influence ...
Laura Orsatti +9 more
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, 2019 Abstrak— This article aims to fulfill administrative duties and educational supervision. Where this article is titled "Administration of special service". This article was created to fulfill the administration and supervision courses. This article is about how special service in the world of education.
openaire +2 more sources
Eclética Química, 2022 The 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (2HMN) is a powerful antibacterial and antiparasitic drug used alongside other drugs against Helicobacter pylori infection and was investigated the effects of substituents: –OH (A), H (B), –SPh (C), –COOH (
Moriam Dasola Adeoye +5 more
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In Silico Pharmacokinetics Study of 2,5-Dibenzylidenecyclopentanone Analogs as Mono-Ketone Versions of Curcumin [PDF]
BIO Web of Conferences, 2023 The absorption-distribution-metabolism-excretion (ADME) profile is a crucial parameter that indicates the pharmacokinetics of the drug. The pharmacokinetic properties of a drug represent the fate of the drug in the body.
Marbun Prajona +4 more
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Toxicity prediction of anti tuberculosis active molecules [PDF]
, 2011 The aim of the work was to understand the toxicity, physically significant descriptors and pharmaceutically relevant properties of some imidazoles obtained from the open sources that may found to be active against tuberculosis.
Abdul Jaleel.U.C, Sajeev R
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ADMET and DMPK, 2018 This review discusses the disposition of the anionic surfactant, sodium dodecyl sulfate (SDS; i.e., sodium lauryl sulfate), to solubilize sparingly-soluble drugs above the surfactant critical micelle concentration (CMC), as quantitated by the ...
Alex Avdeef
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Virtual screening for NS5B inhibitors of Hepatitis C virus [PDF]
, 2012 Hepatitis C Virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at a risk of developing significant morbidity and mortality.
Achuthsankar S. Nair +2 more
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