Results 91 to 100 of about 706,905 (339)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
On Weak Topology for Optimal Control of Switched Nonlinear Systems [PDF]
, 2015 Optimal control of switched systems is challenging due to the discrete nature of the switching control input. The embedding-based approach addresses this challenge by solving a corresponding relaxed optimal control problem with only continuous inputs ...
Chen, Hua, Zhang, Wei
core
On Switched Hamiltonan Systems
, 2002 In this paper we study the well-posedness and stability of a class of switched linear passive systems. Instrumental in our approach is the result, also of interest in its own right, that any linear passive input-state-output system with strictly positive storage function can be written as a port-Hamiltonian system.
Gerritsen, K.M. +2 more
openaire +2 more sources
Robust tracking for functional electrical stimulation cycling with unknown time-varying input delays: A switched systems approach. [PDF]
Front Neurorobot, 2022 Tong X, Zhu Y.
europepmc +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Switched Observer Design for a Class of Non-Linear Systems
Applied System InnovationThis paper is concerned with the switched observer design for a class of systems subject to locally Lipschitz non-linearities. By performing a suitable description of the estimation error dynamics into a linear parameter varying (LPV) system ...
Ivan Francisco Yupanqui Tello +2 more
doaj +1 more source
A Data-Driven Scheme for Fault Detection of Discrete-Time Switched Systems. [PDF]
Sensors (Basel), 2021 Zhao H, Luo H, Wu Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Delay-Independent Stability of Switched Linear Systems with Unbounded Time-Varying Delays
Abstract and Applied Analysis, 2012 This paper is focused on delay-independent stability analysis for a class of switched linear systems with time-varying delays that can be unbounded. When the switched system is not necessarily positive, we first establish a delay-independent stability ...
Yuangong Sun
doaj +1 more source