Results 61 to 70 of about 20,851 (255)
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
High Voltage, 2019 The article proposes a mechanical DC circuit breaker (CB) based on a series LC circuit. It requires two switches (a fast disconnector and an AC circuit breaker), an inductor and a capacitor, and therefore the cost is expected to be low.
Dragan Jovcic
doaj +1 more source
Augmentations and Rulings of Legendrian Knots [PDF]
, 2005 A connection between holomorphic and generating family invariants of Legendrian knots is established; namely, that the existence of a ruling (or decomposition) of a Legendrian knot is equivalent to the existence of an augmentation of its contact homology.
Sabloff, Joshua M.
core +2 more sources
A New Switch and Crossing Design: Introducing the Back to Back Bistable Switch
Journal of Civil Engineering and Construction, 2020 A new track swtich and crossing (S&C), the back to back bistable (B2B) switch, is proposed that has shown potential to significantly reduce the wheel/rail contact forces through the switch due to its more continuous wheel/rail contact interface and more uniform track stiffness arising from the elimination of the crossing nose.
J. -Y. Shih +4 more
openaire +2 more sources
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
MATEC Web of Conferences, 2014 This study relates to the manufacture of austenitic manganese steel for the heart switching crossings of railways in all industrial countries where heavy loads are moved by rail.
Maouche Hichem +2 more
doaj +1 more source
Satellites of Legendrian knots and representations of the Chekanov-Eliashberg algebra
, 2012 We study satellites of Legendrian knots in R^3 and their relation to the Chekanov-Eliashberg differential graded algebra of the knot. In particular, we generalize the well-known correspondence between rulings of a Legendrian knot in R^3 and augmentations
Ng, Lenhard, Rutherford, Dan
core +1 more source
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source
InfrastructuresA sleeper, or more generally a “bearer”, moves vertically under a passing train load. The extent of this motion depends on the static and dynamic load of the train, the train speed, and the support conditions at the bearer and its neighbours.
Jou-Yi Shih +4 more
doaj +1 more source