Results 61 to 70 of about 2,136,839 (361)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Joint time of arrival (TOA) and angle of arrival (AOA) estimation based on a uniform circle array (UCA) involves problems, including high computational complexity in the multi-dimensional spectral search method and lack of applicability in coherent ...
Haiyun Xu +4 more
doaj +1 more source
Task Switching in Predictable and Unpredictable Cases [PDF]
Fourteen experiments have been run in order to provide evidence regarding the cognitive processes that underlie the switching between simple cognitive tasks.
Andreadis, Nikolaos
core
Task switching is not cue switching [PDF]
With the aim of reducing cognitive control in task switching to simpler processes, researchers have proposed in a series of recent studies that there is little more to switching tasks than switching cues. The present study addresses three questions concerning this reduction hypothesis.
openaire +2 more sources
Switching Off the Switch [PDF]
AbstractThe solution structure of the catalytic domain of the dual-specificity phosphatase PAC-1 reveals new insight about the enzymes that deactivate mitogen-activated protein kinases (MAPK).
Selenko, Philipp, Sattler, Michael
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An Underdetermined Source Number Estimation Method for Non-Circular Targets Based on Sparse Array
Source number estimation is one of the key technologies of wireless location, and it is also the basis of parameter estimation and location solution.
Yankui Zhang +4 more
doaj +1 more source
A multi-cell visible light communication (VLC) network with non-orthogonal multiple access (NOMA) introduces an inter-cell interference (ICI), which causes poor experience of overlap-area user association.
Siyu Tao +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

