Results 41 to 50 of about 1,442,659 (301)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Design and Validation of a Model of Customers Switching Barriers in Appliances Industry [PDF]
مطالعات مدیریت راهبردی, 2014 In competitive world where such goods or services offered by competing firms are more similar to each other every day, it is hard to make surprise the customer in long-term via even creative services, because most innovative services quickly imitated by ...
Mitra Mohajeri +3 more
doaj
A survey of E-loyalty effective factors and barriers to E-banking services in private banks customers in Golestan province [PDF]
مدیریت بازرگانی, 2014 The current study aims to identify the effective factors and barriers to loyalty in electronic banking services in the private banks customers. For this purpose, a survey was done with a questionnaire sampling from 420 customers of private banks in ...
Ebrahim Abbasi +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Fast barrier-free switching in synthetic antiferromagnets
Scientific ReportsAbstractWe analytically solve the Landau-Lifshitz equations for the collective magnetization dynamics in a synthetic antiferromagnet (SAF) nanoparticle and uncover a regime of barrier-free switching under a short small-amplitude magnetic field pulse applied perpendicular to the SAF plane.
Yu Dzhezherya +6 more
openaire +4 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Non-volatile optical switch of resistance in photoferroelectric tunnel junctions
Nature Communications, 2021 Designing energy efficient and fast optoelectric neuromorphic systems remains a challenge. Long et al. report that the combined optical-electric stimulus enables switching the ferroelectric polarization and cycling the resistance state of BaTiO3 tunnel ...
Xiao Long +4 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Factors Affecting Mobile Users’ Switching Intentions: A Comparative Study between the Brazilian and German Markets [PDF]
BAR: Brazilian Administration Review, 2013 In the competitive wireless market, there are many drivers behind customer defection. Switching barriers, service performance, perceived value in carriers’ offers, satisfaction and other constructs can play a pivotal role in customer switching processes ...
Rodrigo C. Martins +2 more
doaj
iEnergy, 2022 Simultaneously imposed challenges of high-voltage insulation, high dv/dt, high-switching frequency, fast protection, and thermal management associated with the adoption of 10 kV SiC MOSFET, often pose nearly insurmountable barriers to potential users ...
Slavko Mocevic +17 more
doaj +1 more source