Results 81 to 90 of about 1,442,659 (301)

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Orientation-dependent tunneling electroresistance in Pt/Pb(Zr,Ti)O3/Nb:SrTiO3 ferroelectric tunnel junctions

Journal of Advanced Dielectrics
Orientation anisotropy is a well-known essential character for polarization characteristics of ferroelectric materials, which has been widely investigated in conventional ferroelectric random access memories.
Chunyan Ding, Chunyan Zheng, Weijie Zheng, Chenyu Dong, Yahui Yu, Zheng Wen   +5 more
doaj   +1 more source

Ferroelectric switching in ferroelastic materials with rough surfaces

Scientific Reports, 2019
Electric switching of non-polar bulk crystals is shown to occur when domain walls are polar in ferroelastic materials and when rough surfaces with steps on an atomic scale promote domain switching.
Guangming Lu, Suzhi Li, Xiangdong Ding, Jun Sun, Ekhard K. H. Salje   +4 more
doaj   +1 more source

A computational search for wurtzite-structured ferroelectrics with low coercive voltages

APL Materials, 2020
Ferroelectricity has recently been observed in wurtzite-structured Sc-doped AlN thin films, five years after our initial prediction of ferroelectricity in wurtzite compounds based on first-principles calculations.
Hiroki Moriwake, Rie Yokoi, Ayako Taguchi, Takafumi Ogawa, Craig A. J. Fisher, Akihide Kuwabara, Yukio Sato, Takao Shimizu, Yosuke Hamasaki, Hiroshi Takashima, Mitsuru Itoh   +10 more
doaj   +1 more source

Pengaruh Switching Barriers Terhadap Switching Intention (Survei Pada Konsumen Jne Express Across Nations Di Kota Malang) [PDF]

, 2017
Penelitian ini bertujuan untuk menguji pengaruh switching barriers terhadap switching intention. Switching Barriers adalah faktor-faktor dalam ilmu pemasaran berupa penghalang atau hambatan yang bertujuan untuk mengunci konsumen agar tetap loyal pada ...
Chaidir, AchZulfikar
core  

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Short term entry barriers may be good for long term competition [PDF]

Entry barriers encourage competition “for” the market as opposed to “in” the market. Efficient entrants use penetrating strategies while inefficient incumbents harvest the market before leaving.
Jean-Pierre Ponssard
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Undeveloped coastal barriers: final environmental statement.

, 1983
413 p.This environmental statement analyzes the environmental impacts of actions taken by the Secretary of the Interior pursuant to Part IV of the Omnibus Budget Reconciliation Act of 1981 (OBRA) which prohibited the issuance of new Federal flood ...
U.S. Department of the Interior, Coastal Barriers Task Force
core  

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez, Carmen Espejo, Georgina Arrambide, Mireia Castillo, Marta Rodriguez, Helena Ariño, Iker Elosua, Carmen Tur, Angela Vidal‐Jordana, Andreu Vilaseca, Joaquín Castilló, Ingrid Galán, Luciana Midaglia, Carlos Nos, Breogan Rodríguez‐Acevedo, Ana Zabalza, Luca Bollo, Agustín Pappolla, René Carvajal, Neus Mongay‐Ochoa, Jordi Rio, Jaume Sastre‐Garriga, Manuel Comabella, Gesualdina Busiello, Sofia Sceppacuercia, Àlex Rovira, Xavier Montalban, Mar Tintoré, Cristina Auger, Álvaro Cobo‐Calvo   +29 more
wiley   +1 more source