Results 61 to 70 of about 699,176 (299)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Simulation Studies of Various Structures of Optical Switching Networks

Transport and Telecommunication
The article presents a research of loss probability in various structures of elastic optical network nodes. To conduct the research, an elastic optical networks simulator, which enables to determine loss probabilities of switching network nodes of any ...
Sobieraj Maciej, Tylkowski Mariusz
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A Switch Migration-Based Decision-Making Scheme for Balancing Load in SDN

IEEE Access, 2017
Elastic scaling and load balancing with efficient switch migration are critical to enable the elasticity of software-defined networking (SDN) controllers, but learning how to improve migration efficiency remains a difficult problem. To address this issue,
Chuan'an Wang, Bo Hu, Shanzhi Chen, Desheng Li, Bin Liu   +4 more
doaj   +1 more source

An Efficient Attribute-Based Multi-Keyword Search Scheme in Encrypted Keyword Generation

IEEE Access, 2020
With the growing popularity of cloud computing in recent years, data owners (DOs) now prefer to outsource their data to cloud servers and allow the specific data users (DUs) to retrieve the data.
Yuanbo Cui, Fei Gao, Yijie Shi, Wei Yin, Emmanouil Panaousis, Kaitai Liang   +5 more
doaj   +1 more source

Construction of Neural Network Classification Expert Systems Using Switching Theory Algorithms [PDF]

, 1992
A new family of neural network architectures is presented. This family of architectures solves the problem of constructing and training minimal neural network classification expert systems by using switching theory.
Jaskolski, John V.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An adaptive detection model for IPv6 extension header threats based on deterministic decision automaton

Scientific Reports
The IPv6 extension header mechanism, a new feature of the IPv6 protocol, enhances flexibility and scalability but introduces numerous security threats like firewall evasion and covert channels.
Bin Lin, Liancheng Zhang, Hongtao Zhang, Yi Guo, Shaowei Ge, Yakai Fang, Mingyue Ren   +6 more
doaj   +1 more source

A Human Rights Based Approach to Refugees: A Look at the Syrian Refugee Crisis and the Responses from Germany and the United States [PDF]

, 2014
Power Quality (PQ) has gained a lot of importance in the last decade. Several solutions to power quality problems have been proposed and developed. With the advent of solid state technology and power electronics in the power system protection devices ...
Momin, Suman
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source