Results 91 to 100 of about 3,430,759 (315)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Ethnic Concentration, Cultural Identity and Immigrant Self-Employment in Switzerland [PDF]

Immigrant self-employment rates vary considerably across regions in Switzerland. Business ownership seems to provide an alternative to wage labour, where immigrants have to face structural barriers such as the limited knowledge of the local language, or ...
Giuliano Guerra, Roberto Patuelli, Rico Maggi   +2 more
core   +1 more source

Imagining sufficiency through collective changes as satisfiers

Buildings & Cities
How can people imagine ways of achieving desirable energy futures in cities, oriented towards sufficiency? Building on the notion of sufficiency understood as avoiding demand while meeting human needs, this paper discusses the results of seven ...
Orlane Moynat, Marlyne Sahakian
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Switzerland participates in international efforts to promote sustainable agriculture

, 2019
AGFORWARD, Greenresilient and PERECUSO are international research partnerships developing ways of making agricultural practices more environmentally friendly. Switzerland is participating in these three initiatives through Agroscope, the Swiss centre of
House of, Switzerland
core  

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Cosmopolitan Noises : Atmospheres in Shortwave Radio Listening

Mobile Culture Studies. The Journal, 2017
After World War II, radio as a borderless medium became more and more important as an international agent connecting people worldwide. To date, these transnational connections have been explored primarily in relation to their function as political ...
Patricia, Jäggi
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Stabilization of the prevalence of childhood obesity in Switzerland [PDF]

, 2010
This present study clearly confirms the stabilisation of the prevalence of childhood overweight and obesity in ...
Henschen, Isabelle, Zimmermann, M B, M Zimmermann, Aeberli, I., Zimmermann, Michael B., I Henschen, Isabelle Aeberlia, Aeberli, Isabelle, Molinari, L, L Molinari, Isabelle Henschena, Luciano Molinaric, Aeberli, I, Molinari, Luciano, Henschen, I, Molinari, L., Zimmermann, M.B., Henschen, I., I Aeberli, Michael B. Zimmermanna   +19 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source