Results 71 to 80 of about 5,122,879 (337)

Older Refugees: Strategies in Dealing With Denied Recognition

open access: yesSwiss Journal of Sociology, 2020
Until now the topic linking age and the moment of fleeing one’s country of origin have been of scientific interest only rarely. Older refugees have hardly attracted scientific attention.
Jurt Luzia, Sperisen Vera
doaj   +1 more source

Negotiating Vertical Urbanization at the Public–Private Nexus: On the Institutional Embeddedness of Planning Committees

open access: yesUrban Planning, 2022
While the planning and development of dense and high-rise neighborhoods are commonly perceived as primarily technical procedures, the past several decades have highlighted the growing social complexity of these processes.
Johannes Herburger   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Digital competencies in medical education in Switzerland: an overview of the current situation

open access: yesGMS Journal for Medical Education, 2020
Background: Today’s medical students are growing up in a digital age in which the use of smartphones and smart devices is now irrevocably part of professional life.
Hautz, Stefanie C.   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Natural hazard fatalities in Switzerland from 1946 to 2015

open access: yes, 2016
. A database of fatalities caused by natural hazard processes in Switzerland was compiled for the period between 1946 and 2015. Using information from the Swiss flood and landslide damage database and the Swiss destructive avalanche database, the data ...
A. Badoux   +3 more
semanticscholar   +1 more source

The "Profiles" document: a modern revision of the objectives of undergraduate medical studies in Switzerland.

open access: yesSwiss medical weekly, 2016
The Joint Commission of the Swiss Medical Schools (SMIFK/CIMS) decided in 2000 to establish a Swiss Catalogue of Learning Objectives (SCLO) for undergraduate medical training, which was adapted from a similar Dutch blueprint. A second version of the SCLO
P. Michaud   +2 more
semanticscholar   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Innovations in Journalism as Complex Interplay: Supportive and Obstructive Factors in International Comparison

open access: yesMedia and Communication
Where does innovation in journalism come from, how is it implemented, and what factors drive or hinder its development? Scholars have explored these questions from different perspectives for over two decades.
Klaus Meier   +9 more
doaj   +1 more source

Excess mortality during the warm summer of 2015 in Switzerland.

open access: yesSwiss medical weekly, 2016
QUESTION UNDER STUDY In Switzerland, summer 2015 was the second warmest summer for 150 years (after summer 2003). For summer 2003, a 6.9% excess mortality was estimated for Switzerland, which corresponded to 975 extra deaths.
A. Vicedo-Cabrera   +3 more
semanticscholar   +1 more source

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