Results 61 to 70 of about 5,122,879 (337)
Scandinavian Journal of Work, Environment & HealthOBJECTIVE: This study aimed to investigate the effect of a 12-week multi-component intervention on neck pain among Swiss office workers. METHODS: Between January 2020 and April 2021, we conducted a stepped-wedge cluster randomized controlled trial ...
Andrea Martina Aegerter +8 more
doaj +1 more source
Life expectancy in HIV-positive persons in Switzerland: matched comparison with general population
AIDS (London), 2016 Objectives: To estimate life expectancy over 25 years in HIV-positive people and to compare their life expectancy with recent estimates for the general population, by education.
Aysel Gueler +11 more
semanticscholar +1 more source
Resurgence of HIV infection among men who have sex with men in Switzerland : mathematical modelling study [PDF]
, 2012 New HIV infections in men who have sex with men (MSM) have increased in Switzerland since 2000 despite combination antiretroviral therapy (cART). The objectives of this mathematical modelling study were: to describe the dynamics of the HIV epidemic in ...
Bezemer, Daniela +12 more
core +5 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Enforcing the rights of migrants with irregular status: City ID cards as a remedy?
Cognitio, 2021 Migrants who live in Switzerland without valid residence papers find themselves in a complex and contradictory legal position. Even though they are entitled to a great number of rights, they are rarely able to claim them in practice.
Irina Fehr
doaj +1 more source
Opportunities for farming in alpine countries – pathways to truly grassland-based beef and milk production in Austria and Switzerland [PDF]
, 2018 Farming in the alpine countries of Austria and Switzerland fulfils important economic, socio-cultural and ecological functions for society. However, even though both Austria and Switzerland have increasingly focused their agricultural policy towards ...
Bartel, A. +7 more
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Information Guide: Switzerland [French] - Guide d’information: Suisse [PDF]
, 2016 Un guide de sources d’information sur la Confédération ...
EDC, Cardiff
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source