Results 51 to 60 of about 3,263,150 (264)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Typology of children media users
Studies in Communication Sciences, 2023 Research about children’s media use is often concerned with the effects of one particular medium. There is rather little research about more general media diets in terms of their diversity and the resulting outcomes. Against the theoretical background of
Hannah Früh, Andreas Fahr
doaj +1 more source
Flying Less for Work and Leisure? Co-Designing a City-Wide Change Initiative in Geneva
Urban Planning, 2021 Geneva prides itself on being an international city, home to the United Nations and international organizations. The airport plays an important role in this image, tied to a quest for hypermobility in an increasingly globalized society.
Marlyne Sahakian +4 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Unravelling the Entoloma politum complex
Plant and Fungal Systematics, 2023 Entoloma politum is a common lowland species in northern Europe. It has been described to have two close species with a more intense smell, E. nitriolens and E. pernitrosum . To clarify the taxonomy of these three species, the types of E. nitriolens
Katri Kokkonen
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Evolution of a field: Swiss media and communication studies
Studies in Communication Sciences, 2019 In this paper, we present the evolution of Swiss Media and Communication Studies over the last decade by summarizing the main results from a project funded by the Swiss University Conference (2008–2017).
Carole Probst +3 more
doaj +1 more source
The Image of a Tree in F.M. Dostoyevsky's Novel "The Idiot" [PDF]
Достоевский и мировая культура: Филологический журнал, 2018 The article is devoted to the analysis of the image of a tree in Dostoevsky’s novel “The Idiot”. The author reflects on the evolution of this image from an artistic detail in the description of the Pavlovsk Park to the philosophical symbol of the Golden ...
Olga N. Smyslova
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source