Results 101 to 110 of about 278,985 (299)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Analysis of Consumer Behavior Toward Increased Sales of Orgamas Liquid Organic Fertilizer Products
Agricultural Science, 2020 This study aims to determine: 1. Knowing the response and interest of farmers to the products of Organic Liquid Organic Fertilizer Orgamas in the Dawarblandong area. 2.
Budi Utomo, Steffan Albert
doaj
Identification and Prioritization of Tourism Development Strategies in Shiraz Applying SWOT technique and ANP model [PDF]
جغرافیا و پایداری محیط, 2015 The present study aims at recognizing and prioritizing tourism development strategies of Shiraz applying SWOT technique and ANP model. This research is a descriptive-analytical one with deductive logic using field and document methods. First of all, SWOT
Mohammad Gholami +3 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Baseline Assessment: Alaska's Capacity and Infrastructure for Prescription Opioid Misuse Prevention [PDF]
, 2017 The State of Alaska Department of Health and Social Services (DHSS), Division of Behavioral Health (DBH) was awarded the Partnerships for Success (PFS) grant by the Substance Abuse and Mental Health Services Administration (SAHMSA) in 2015.
Barnett, Jodi +3 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
STRATEGIC ORIENTATION OF BUSINESS ORGANIZATION – STEP BY STEP [PDF]
Journal of Bio-Based Marketing, 2020 Every business strategy exists to achieve certain objectives. The global objective of business enterprises is to make new consumers or to create new values for customers (Drucker).
Petar Borisov, Arberesha Behluli
doaj
Learning our way towards a sustainable agri-food system Three cases from Sweden: Stockholm Farmers market, Ramsjö Community Supported Agriculture and Järna Initiative for Local Production [PDF]
, 2003 This research is based on case studies of the Stockholm Farmers Market, Ramsjö Community Supported Agriculture, and Järna Initiative for Local Production. These cases are examples of alternative consumerproducer links in the Swedish agri-food system.
Adler, Steffen +3 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Open Agriculture, 2017 Smallholders in Eastern and Southern Africa(ESA) have limited access to timely availability of quality sweetpotato seed which contributes to sub-optimal root yields.
Rajendran Srinivasulu +2 more
doaj +1 more source