Results 81 to 90 of about 146,307 (259)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

The Application of Analyses in Industrial Commodity Trade in Croatia

open access: yesActa Economica et Turistica, 2021
After the corona virus pandemic is over, we can expect significant changes in management systems due to a further decrease in industrial commodity trade and, simultaneously, an increase in service trade, digital technology services in particular.
Zvonko Merkaš   +2 more
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Применение SWOT-анализа для планирования стратегического развития фирмы

open access: yes, 2016
Название выпускной квалификационной работы: применение SWOT-анализа для планирования стратегического развития фирмы Автор: Поклонская Е.А., бакалавриант 4 курса Научный руководитель: Артемова Д.И.
Поклонская Екатерина Александровна   +1 more
core  

Strategic Planning of Medical Tourism with an Emphasis on Religious Tourism in Mashhad City

open access: yesتحقيقات جغرافيايی, 2016
Medical tourism is a branch of health tourism that has grown considerably in many parts of the world now days. Mashhad city with regard to  the Holy Shrine, More than 300 thousand foreign tourists per year, more than 31 public and private hospitals and ...
Ali Hajinejad   +2 more
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Estimation of the value of forest ecosystem services to develop conservational strategy management (strengths, weaknesses, opportunities and threats)

open access: yesJournal of Forest Science, 2017
Forests ecosystems provide several undisputable benefits which policy-makers blink since these values do not record in conventional markets or are difficult to measure.
Komeil JAHANIFAR   +3 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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