Results 121 to 130 of about 22,068,560 (401)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

SWOT-analysis in the management system of higher educational institution

RUDN Journal of Informatization in Education, 2011
The article considers method of SWOT-analysis - pedagogical activity. The essence of method of SWOT-analysis is shown.
G N Gubaydullina
doaj  

Analysis of Marketing Mix Strategies in Increasing Sales Volume of Tempong Food Stall Surabaya

Indonesian Interdisciplinary Journal of Sharia Economics
This study aims to identify the marketing strategies used by Kedai Tempong Surabaya to increase sales volume. The sampling method was carried out purposively by evaluating the implementation of the 7P marketing mix strategy (product, price, place ...
Rifqi Agata Geovani Pratama, Budi Prabowo   +1 more
doaj   +1 more source

SWOT analysis of Ukraine’s transport industry [PDF]

MATEC Web of Conferences
The study conducted a critical analysis of scientific research and methods of strategic planning and determined that SWOT analysis is one of the effective tools.
Novikova Alla, Lytvynenko Sergiy, Yashchenko Tetyana, Voitsehovskiy Viktor, Dehtiar Zoia, Ovchar Petro   +5 more
doaj   +1 more source

PENERAPAN ANALISIS SWOT DAN TOTAL QUALITY MANAGEMENT (TQM) DALAM MENINGKATKAN STRATEGI PEMASARAN PT LOKA FIBER [PDF]

This research focuses on the application of SWOT Analysis and Total Quality Management (TQM) in improving the case study marketing strategy at PT Loka Fiber. The research method used was qualitative research, the sample in this study consisted of 4
Bilqis, Diana
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Swot–анализ как способ стратегического планирования конкурентоспособности туристического предприятия

Туризм и гостеприимство, 2016
SWOT–анализ является элементом стратегического планирования конкурентоспособности туристического предприятия. В статье отражены основные этапы проведения анализа, выявлены факторы, характеризующие внешнюю и внутреннюю среду регионального туристического ...
Т.Г. Жолох (T.G. Zholoh), А.О. Васильченко ( A.O. Vasilchenko)   +1 more
doaj  

What use are formal design and analysis methods to telecommunications services? [PDF]

, 1998
Have formal methods failed, or will they fail, to help us solve problems of detecting and resolving of feature interactions in telecommunications software?
Calder, M.
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source