Results 71 to 80 of about 22,068,560 (401)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

SWOT analysis and GUT matrix for business management and problem solving: an application in a Brazilian case-study

open access: yesCuadernos de Gestión, 2022
The present research aims to use SWOT analysis to identify strategic problems of small business companies (SBCs) from the automotive selling parts of a brazilian city and use the GUT matrix for identifying a Priority Level (PL) result of each problem ...
José André Villas Boas Mello   +2 more
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

A SWOT Analysis of Planning Support Systems [PDF]

open access: yesEnvironment and Planning A: Economy and Space, 2007
Insight into the strengths, weaknesses, opportunities, and threats (SWOT) of planning support systems (PSS) is fragmented between users and system developers. The lack of combined insights blocks development in the right direction and makes potential users hesitant to apply PSS in planning.
Guido Vonk, Stan Geertman, Paul Schot
openaire   +5 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

SWOT ANALYSIS: THE TECHNIQUE [PDF]

open access: yesВестник Тверского государственного университета. Серия: Экономика и управление, 2020
В статье представлен наиболее распространенный метод анализа - SWOT-анализ, позволяющий предприятию проанализировать состояние внешней и внутренней среды, выявить возможности и угрозы, свои сильные и слабые стороны. Одновременно он дает возможность разработать мероприятия, позволяющие предприятию адаптироваться к изменениям среды.
openaire   +1 more source

SWOT Analysis of Nursing Clinic Professional Career Ladder System (SJKP2K) in Military Hospital Jakarta [PDF]

open access: yes, 2018
Nursing managers must have a strong directing function towards the Professional Clinic Nurse Career Ladder System (SJKP2K). This is to improve the quality of nursing care that will be provided by nurses to patients.
Anisah, S. (Siti)   +2 more
core  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

When David turns out to be Goliath... and vice versa [PDF]

open access: yes, 2008
The tool SWOT is introduced as being one element of the overall Marketing Plan and Planning Process. The companies “Fisherman’s Friend” (FF) and the “Smart Micro Compact Car GmbH” (Smart) are used to illustrate a more or less successful application of ...
Sedtke, Dirk
core  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

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