Results 81 to 90 of about 66,885 (279)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
SWOT ANALYSIS OF UNDERGRADUATE AND POSTGRADUATE MEDICAL TRAINING PROGRAMS IN OCCUPATIONAL HEALTH
Objectives. Carrying out SWOT analysis of undergraduate and postgraduate training programs to identify factors that may affect the quality, sustainability, and relevance of the program, with the aim of contributing to the training of occupational health ...
Serghei CEBANU +4 more
core +1 more source
Analisis Strategi Pengembangan Usaha Minuman Sari Buah Sirsak
Industria: Jurnal Teknologi dan Manajemen Agroindustri, 2017 Abstrak Usaha kecil menengah minuman sari buah sirsak termasuk dalam bidang pengolahan pangan. Dalam realitasnya usaha ini banyak mengalami permasalahan terutama dalam hal pengembangan usaha supaya mampu bertahan dalam persaingan bisnis.
Miftakhurrizal Kurniawan, Novi Haryati
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Microneedles in cosmetology: A SWOT analysis
European Journal of Medicinal Chemistry ReportsBackground: Cosmetic microneedling has emerged as a popular minimally invasive technique. This systematic review employs the SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis framework to comprehensively evaluate the current landscape of ...
Shweta Singh +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Cognitive Resilience Education in the Czech Military: SWOT Analysis
This article presents the first systematic analysis of cognitive resilience education within the Czech Ministry of Defence, which is growing in importance in the context of contemporary hybrid threats.
Vendula Divišová +3 more
core +1 more source
A SWOT Analysis of Modular Construction
EncyclopediaModular construction is generally defined as a typical offsite construction approach that can improve environmental sustainability throughout the building project lifecycle.
Zhenquan Zhou +3 more
doaj +1 more source