Results 81 to 90 of about 64,964 (336)

PLXDC1+ Tumor‐Associated Pancreatic Stellate Cells Promote Desmoplastic and Immunosuppressive Niche in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
This study uncovers the activation, heterogeneity, and regulatory roles of pancreatic stellate cells (PSCs) at single‐cell and spatial levels. It further identifies PLXDC1+ PSCs near aggressive LRRC15+ cancer‐associated myofibroblasts and SPP1+ macrophages, forming a desmoplastic and immunosuppressive tumor niche that promotes CD8+ T cell exhaustion ...
Yanhua Du, Yizhou Zhao, Judong Li, Jiaxin Wang, Shenglan You, Yao Zhang, Li Zhang, Jihong Yang, Hamid Alinejad‐Rokny, Shujie Cheng, Chenghao Shao, Duowu Zou, Youqiong Ye   +12 more
wiley   +1 more source

N and P constrain C in ecosystems under climate change: Role of nutrient redistribution, accumulation, and stoichiometry

Ecological Applications, Volume 32, Issue 8, December 2022., 2022
Abstract We use the Multiple Element Limitation (MEL) model to examine responses of 12 ecosystems to elevated carbon dioxide (CO2), warming, and 20% decreases or increases in precipitation. Ecosystems respond synergistically to elevated CO2, warming, and decreased precipitation combined because higher water‐use efficiency with elevated CO2 and higher ...
Edward B. Rastetter, Bonnie L. Kwiatkowski, David W. Kicklighter, Audrey Barker Plotkin, Helene Genet, Jesse B. Nippert, Kimberly O'Keefe, Steven S. Perakis, Stephen Porder, Sarah S. Roley, Roger W. Ruess, Jonathan R. Thompson, William R. Wieder, Kevin Wilcox, Ruth D. Yanai   +14 more
wiley   +1 more source

The Nuclear Jet in M81 [PDF]

, 1996
In this paper we apply the jet-disk symbiosis model developed for Sgr A* to M81* -- the nucleus of the nearby galaxy M81. The model accurately predicts radio flux and size of M81* for the observed bolometric luminosity of the nuclear source with no major free parameter except for the inclination angle.
arxiv   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

Advanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang, Longfei Li, Yiran Hu, Zhou Li, Wei Hua   +4 more
wiley   +1 more source

Absence of stress‐promoted facilitation coupled with a competition decrease in the microbiome of ephemeral saline lakes

Ecology, Volume 103, Issue 12, December 2022., 2022
Abstract Salinity fluctuations constitute a well‐known high stress factor strongly shaping global biological distributions and abundances. However, there is a knowledge gap regarding how increasing saline stress affects microbial biological interactions.
Mateu Menéndez‐Serra, Vicente J. Ontiveros, Albert Barberán, Emilio O. Casamayor   +3 more
wiley   +1 more source

Atomic Symbiotic‐Catalyst for Low‐Temperature Zinc‐Air Battery

Angewandte Chemie, EarlyView.
A new “atomic symbiotic‐catalyst” system comprising single‐atom MNx and local sp3 carbon defects is proposed, which marries the advantages of typical single‐/dual‐atom catalysts while addressing their respective weaknesses, thus synergistically achieves high electrocatalytic activity and battery efficiency.
Ge Meng, Zaimei Huang, Lei Tao, Zechao Zhuang, Qingcheng Zhang, Qilin Chen, Hui Yang, Huaping Zhao, Chenliang Ye, Yu Wang, Jian Zhang, Wei Chen, Shixuan Du, Yihuang Chen, Dingsheng Wang, Huile Jin, Yong Lei   +16 more
wiley   +2 more sources

Overcoming Extreme Ammonia Inhibition on Methanogenesis by Artificially Constructing a Synergistically Community with Acidogenic Bacteria and Hydrogenotrophic Archaea

Advanced Science, EarlyView.
This study proposes a two‐step biological strategy to synergistically enhance the three stages of anaerobic digestion, ultimately eliminating the extreme ammonia inhibition and breaking through the inefficiency bottleneck of conventional biotechnology.
Heng Wu, Huaiwen Zhang, Taili Dong, Zhenyu Li, Xiaohui Guo, Heyu Chen, Yiqing Yao   +6 more
wiley   +1 more source

Artificial microbial consortia for bioproduction processes

Engineering in Life Sciences, Volume 23, Issue 1, January 2023., 2023
Abstract The application of artificial microbial consortia for biotechnological production processes is an emerging field in research as it offers great potential for the improvement of established as well as the development of novel processes. In this review, we summarize recent highlights in the usage of various microbial consortia for the production
Fabian Mittermeier, Miriam Bäumler, Prasika Arulrajah, José de Jesús García Lima, Sebastian Hauke, Anna Stock, Dirk Weuster‐Botz   +6 more
wiley   +1 more source

Ultra‐Low Density Covalent Organic Framework Sponges with Exceptional Compression and Functional Performance

Angewandte Chemie, EarlyView.
The construction method for the hierarchical porous covalent organic framework (COF) sponges with hollow cell walls through a template‐assisted framework solvothermal process is shown. The COF sponges exhibit ultralow density (2.2 mg cm−3), high surface area (1655 m2 g−1), and unprecedented compression performance (demonstrated by only a 7.9% decrease ...
Chenhui Ding, Yingying Du, Tamara Fischer, Jürgen Senker, Seema Agarwal   +4 more
wiley   +2 more sources

An empirical study of the naïve REINFORCE algorithm for predictive maintenance

Discover Applied Sciences
Reinforcement Learning (RL) is a biologically inspired, autonomous machine learning method. RL algorithms can help generate optimal predictive maintenance (PdM) policies for complex industrial systems. However, these algorithms are extremely sensitive to
Rajesh Siraskar, Satish Kumar, Shruti Patil, Arunkumar Bongale, Ketan Kotecha, Ambarish Kulkarni   +5 more
doaj   +1 more source