Results 31 to 40 of about 51,667 (267)
Financial markets give a large number of trading opportunities. However, over-complicated systems make it very difficult to be effectively used by decision-makers.
Jan Kozak +2 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Universally Composable Symbolic Security Analysis [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Canetti, Ran, Herzog, Jonathan
openaire +2 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Identifying Ordinal Similarities at Different Temporal Scales
This study implements the permutation Jensen–Shannon distance as a metric for discerning ordinal patterns and similarities across multiple temporal scales in time series data.
Luciano Zunino +2 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Symbolic analysis of linear electric circuits with MIT Julia Symbolics.jl package [PDF]
This paper presents novel free open-source software JuliaCAP for symbolic analysis of linear time-invariant electric circuits in the complex domain of the Unilateral Laplace Transform or Phasor Transform. Modified Nodal Analysis (MNA) has been chosen for
Došlo Glorija Z., Rajković Kristina D.
doaj +1 more source
Control-Flow Residual Analysis for Symbolic Automata [PDF]
Where full static analysis of systems fails to scale up due to system size, dynamic monitoring has been increasingly used to ensure system correctness.
Shaun Azzopardi +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source

