Results 51 to 60 of about 42,583 (307)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Signs and Symbolic Behavior

open access: yesBiological Theory, 2014
Research in archaeology and anthropology on the evolution of modern patterns of human behavior often makes use of general theories of signs, usually derived from semiotics. Recent work generalizing David Lewis’ 1969 model of signaling provides a better theory of signs than those currently in use.
openaire   +2 more sources

The Origin of a Symbol in Animal Behaviors.

open access: yesSeibutsu Butsuri, 2002
This report discusses how one can argue the origin of a symbol in animal behaviors, with respect to experiments and models. The results suggest that the frame-problem resulting in the power-law positively plays a role in the origin of a symbol.
GUNJI, Yukio-Pegio   +2 more
openaire   +2 more sources

Symbolic Analysis of OTRAs-Based Circuits [PDF]

open access: yes, 2011
A new nullor-based model to describe the behavior of Operational Transresistance Amplifiers (OTRAs) is introduced. The new model is composed of four nullors and three grounded resistors. As a consequence, standard nodal analysis can be applied to compute
ESTEBAN TLELO CUAUTLE   +2 more
core  

The emergence of symbolic norms

open access: yes, 2023
Human groups are experts in developing and maintaining social norms. Many social norms have clear practical functions, such as regulating competition or facilitating coordination.
Pan, Xinyue
core   +1 more source

Method of Symbolic Test Scenarios Automated Concretization

open access: yesТруды Института системного программирования РАН, 2018
Described in the paper is an approach to symbolic test scenarios concretization in the scope of automated software verification and testing technology. Tools for automated concretization process based on user defied settings are presented.
Nikita V. Voinov   +4 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Layanan Penguasaan Konten dengan Teknik Symbolic Modelling untuk Meningkatkan Perilaku Prososial Siswa

open access: yesPsychocentrum Review, 2019
Mastery content service is one of the guidance and counseling topic that is quite familiar in Indonesia to facilitate participants mastering a current series of competences.
Ana Rahmatun Khasanah   +2 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Effects of spatial and symbolic precues on localization performance

open access: yes, 2000
One of the fundamental properties of spatial vision is the ability to localize objects in space. According to a recent proposal, accurate localization performance involves the operation of two systems: the attention system and the eye movement system ...
van Loon, E.M.   +9 more
core   +1 more source

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