Results 41 to 50 of about 33,861 (297)
BMC Veterinary ResearchBackground Common marmosets (Callithrix jacchus) are widely used as primate experimental models in biomedical research. Duodenal dilation with chronic vomiting in captive common marmosets is a recently described life-threatening syndrome that is ...
Shinpei Kawarai +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Fetal Heart Rate Fragmentation
Frontiers in Pediatrics, 2021 Intrapartum fetal monitoring's primary goal is to avoid adverse perinatal outcomes related to hypoxia/acidosis without increasing unnecessary interventions.
Matilde Costa +6 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
BMC Psychiatry, 2011 Background The role of psychotherapy in the treatment of traumatic brain injury is receiving increased attention. The evaluation of psychotherapy with these patients has been conducted largely in the absence of quantitative data concerning the therapy ...
Gilpin Adele MK +4 more
doaj +1 more source
A symbolic projection of Langton's Ant [PDF]
Discrete Mathematics & Theoretical Computer Science, 2003 The Langton's ant is studied from the point of view of topological dynamical systems. A new approach which associate a subshift to the system is proposed.The transition rule is generalized to the family of bi-regular graphs $\Gamma(k,d)$ and the ...
Anahi Gajardo
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
From symbolic dynamics to a digital approach [PDF]
, 2001 We show that the numbers generated by the symbolic dynamics of Feigenbaum attractors are transcendental. Due to the asymmetry of the chaotic attractors of unimodal maps around the maximum in the general case, a standard conjecture, that the occurrence of
Karamanos, Konstantinos
core +1 more source
Fractal and Fractional, 2022 To further understand the dynamical characteristics of chaotic systems with a hidden attractor and coexisting attractors, we investigated the fundamental dynamics of a novel three-dimensional (3D) chaotic system derived by adding a simple constant term ...
Chengwei Dong
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source