Results 61 to 70 of about 451,542 (281)
Dynamical behavior of a parametrized family of one-dimensional maps
Electronic Journal of Qualitative Theory of Differential Equations, 2022 The connection of these maps to homoclinic loops acts like an amplifier of the map behavior, and makes it interesting also in the case where all map orbits approach zero (but in many possible ways).
Erkan Muştu
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Heart Rate Fragmentation: A Symbolic Dynamical Approach
Frontiers in Physiology, 2017 Background: We recently introduced the concept of heart rate fragmentation along with a set of metrics for its quantification. The term was coined to refer to an increase in the percentage of changes in heart rate acceleration sign, a dynamical marker of
Madalena D. Costa +2 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Nonlinear causal influences assessed by mutual compression entropy
Current Directions in Biomedical Engineering, 2016 Autonomic control of the heart rate was demonstrated to be complex and nonlinear. Respiratory sinus arrhythima plays a crucial role in heart rate vagal modulation.
Schumann Andy +2 more
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Современные информационные технологии и IT-образование, 2021 The proposed article examines the methodology for developing students' thinking flexibility by combining various approaches to the implementation of educational mathematical tasks.
Valeriy Sekovanov +3 more
doaj +1 more source
Symbolic dynamics I. Finite dispersive billiards
, 1993 Orbits in different dispersive billiard systems, e.g. the 3 disk system, are mapped into a topological well ordered symbol plane and it is showed that forbidden and allowed orbits are separated by a monotone pruning front.
Hansen, Kai T.
core +1 more source
, 2015 We introduce a theory of timed symbolic dynamics unifying results from timed automata theory and symbolic dynamics. The timed sofic shift spaces we define are a way of seeing timed regular languages as shift spaces on general alphabets (in classical symbolic dynamics, sofic shift spaces correspond to regular languages).
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source