Results 81 to 90 of about 4,968 (249)

Conjunctive block coding for hyperdimensional graph representation

Intelligent Systems with Applications
Knowledge Graphs (KGs) have become a pivotal knowledge representation tool in machine learning, not only providing access to existing knowledge but also enabling the discovery of new knowledge through advanced applications.
Ali Zakeri, Zhuowen Zou, Hanning Chen, Hugo Latapie, Mohsen Imani   +4 more
doaj   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Architecture and Armour in Heritage Discourse: Form, Function, and Symbolism

Heritage
This article proposes a comparative framework for interpreting architectural and armorial artefacts through morphological and symbolic analysis. Focusing on the Romanesque, Gothic, and Renaissance periods, the study explores how buildings and body armour—
Adrian Horațiu Pescaru, Ivett-Greta Zsak, Iasmina Onescu   +2 more
doaj   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

De ollitas y paredes volteadas a urnas y monumento patrimonial. La Comunidad India de Quilmes y las resignificaciones del sitio arqueológico a partir de la reconstrucción

Nuevo mundo - Mundos Nuevos, 2012
In this paper we aim to reflect about the role/link that the different materialities associated to the archaeological site called Sacred City of Quilmes play (and have played) in the past and present development of the Indian Community of Quilmes.
María Florencia Becerra, María Victoria Pierini, Lorena B. Rodríguez, Bettina Sidy, Sandra Tolosa   +4 more
doaj   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Поиск географии и путей формирования мифоритуальной символики железа у населения Северного Причерноморья по данным археологии / Research of the geography and ways of formation of mythological and ritual symbolism of the iron at the population of the Northern Black Sea coast according to archaeological data

Tyragetia, 2016
Based on archaeological evidence about ancient nonferrous and ferrous metallurgy, from the Bronze Age to the Middle Ages, the author discusses perspectives in search of possible ways of forming of mythological and sacral aspects of iron symbolism in ...
Nikolay Tupchienko
doaj  

Projection and Reconstruction in Symbolic Interpretation

This paper serves as the theoretical precursor to “Before Language” and the DBCQTL architecture.
openaire   +2 more sources

Reconstructing early human symbolic evolution using transmission experiments.

, 2023
Engraved ochres and ostrich eggshells from the South African Blombos Cave and Diepkloof Rock Shelter are among the earliest expressions of human symbolic behavior. Furthermore, they appear to document a continuous practice of abstract mark-making across ~40.000 years.
Tylen, Kristian, Qvist, Aske Svane, Kjeldsen, Rebecca Foss, Rojo, Sergio, Heimann, Katrin, Fay, Nicolas, Johannsen, Niels N., Riede, Felix, Lombard, Marlize, Fusaroli, Riccardo   +9 more
openaire   +2 more sources

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source