Results 71 to 80 of about 7,296,413 (350)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Symmetrical Immune Network Theory and a New HIV Vaccine Concept [PDF]

, 2010
The symmetrical immune network theory is based on Jerne’s network hypothesis. An improved version of the theory is presented. The theory is characterized by symmetrical stimulatory, inhibitory and killing interactions between idiotypic and ...
Geoffrey W. Hoffmann
core   +1 more source

Application of a strong FSI coupling scheme for the numerical simulation of bileaflet mechanical heart valve dynamics: study of wall shear stress on the valve leaflets [PDF]

, 2012
One of the major challenges in the design of Bileaflet Mechanical Heart Valves (BMHVs) is reduction of the blood damage generated by non-physiological blood flow.
Annerel, Sebastiaan, Claessens, Tom, Dahl, Sigrid Kaarstad, Degroote, Joris, Hellevik, Leif Rune, Segers, Patrick, Skallerud, Bjorn, Van Ransbeeck, Peter, Verdonck, Pascal, Vierendeels, Jan   +9 more
core   +1 more source

False head complexity and evidence of predator attacks in male and female hairstreak butterflies (Lepidoptera: Theclinae: Eumaeini) from Mexico [PDF]

PeerJ, 2019
In many butterfly species, the posterior end of the hindwings of individuals perching with their wings closed resembles a butterfly head. This “false head” pattern is considered an adaptation to deflect predator attacks to less vulnerable parts of the ...
Eric Novelo Galicia, Moisés Armando Luis Martínez, Carlos Cordero   +2 more
doaj   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A Symmetric Free Energy Based Multi-Component Lattice Boltzmann Method

, 2007
We present a lattice Boltzmann algorithm based on an underlying free energy that allows the simulation of the dynamics of a multicomponent system with an arbitrary number of components. The thermodynamic properties, such as the chemical potential of each
A. J. Wagner, Qun Li, R. Jones
core   +1 more source

Subliminal galvanic-vestibular stimulation influences ego- and object-centred components of visual neglect [PDF]

, 2014
Neglect patients show contralesional deficits in egocentric and object-centred visuospatial tasks. The extent to which these different phenomena are modulated by sensory stimulation remains to be clarified. Subliminal galvanic vestibular stimulation (GVS)
Karbach, Julia, Keller, Ingo, Kerkhoff, Georg, Oppenlaender, Karin, Oppenländer, Karin, Reinhart, Stefan, Schindler, Igor   +6 more
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Sensitivity analysis of a single phase to ground fault system in connection with high impedance faults: A case study

Cogent Engineering, 2020
Most of High-impedance faults (HIFs) occur due to broken conductors falling on high-resistivity desert soil in United Arab Emirates remain undetected due to incredibly low fault currents and endanger lives. A reliable detection method is needed.
Perumal Velmurugan, Adhir Baran Chattopadhayay   +1 more
doaj   +1 more source

Advanced symmetrical components method

IET Generation, Transmission & Distribution, 2011
The article deals with symmetrical components method applied for the calculation of (a)symmetrical steady states of three-phase (un)balanced networks. When one considers these states, they are faced with the choice between two undesirable things: (i) to stay in the phase domain and cope with huge number of inductive and capacitive couplings inside ...
openaire   +1 more source