Results 51 to 60 of about 7,595 (197)

The Method of High Accuracy Calculation of Robot Trajectory for the Complex Curves

open access: yesManagement Systems in Production Engineering, 2020
The geometric model accuracy is crucial for product design. More complex surfaces are represented by the approximation methods. On the contrary, the approximation methods reduce the design quality. A new alternative calculation method is proposed.
Lozhkin Alexander   +2 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Learning Inverse Statics Models Efficiently With Symmetry-Based Exploration

open access: yesFrontiers in Neurorobotics, 2018
Learning (inverse) kinematics and dynamics models of dexterous robots for the entire action or observation space is challenging and costly. Sampling the entire space is usually intractable in terms of time, tear, and wear.
Rania Rayyes, Daniel Kubus, Jochen Steil
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Conservation laws that depend on functions and PDE reduction: Extending Noether $1\tfrac {1}{2}$

open access: yesEuropean Journal of Applied Mathematics
This paper develops methods for simplifying systems of partial differential equations (PDEs) that have families of conservation laws which depend on arbitrary functions of the independent or dependent variables. Cases are identified in which such methods
Peter E. Hydon, John R. King
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Solving an isotropic grey matter tumour model via a heat transfer equation

open access: yesOpen Physics
The prevalence and growth characteristics of glioma tumours in human tissues are often modelled by a parabolic partial differential equation. It is essential to analyse tumour growth factors to establish mathematical benchmarks in understanding cancer ...
Jamal Sameerah
doaj   +1 more source

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