Results 31 to 40 of about 1,852,152 (244)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Symmetry of system and system of symmetry
AbstractRelation “symmetry-system” is investigated from the point of view of the author's version of general systems theory (GST(U)). The symmetry of system is explicated in three ways: (i) in the form of the theory of groups of nonevolutionary and evolutionary system transformations and their invariants, (ii) in the form of a proof of symmetry of the ...
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(29 pages)
Babelon, Olivier, Bernard, Denis
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Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel+3 more
wiley +1 more source
This note begins with an introduction to the inverse isospectral problem popularized by M. Kac's 1966 article in the American Mathematical Monthly, "Can one hear the shape of a drum?" Although the answer has been known for some twenty years now, many open problems remain.
Lu, Z., Rowlett, J.
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The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley +1 more source
Differences between the quantum mechanical and relativistic concepts of time observed in GPS satellites are accounted for by applying the equivalence principle to the transitioning electron of an atomic clock. This allows a differential equation of motion to be derived for the electron in the Minkowski space between electron shells.
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The low-lying spectra of atomic nuclei display diverse behaviors, for example rotational bands, which can be described phenomenologically by simple symmetry groups such as spatial SU(3). This leads to the idea of dynamical symmetry, where the Hamiltonian commutes with the Casimir operator(s) of a group, and is block-diagonal in subspaces defined by the
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Symmetry, Structure and the Constitution of Objects [PDF]
In this paper I focus on the impact on structuralism of the quantum treatment of objects in terms of symmetry groups and, in particular, on the question as to how we might eliminate, or better, reconceptualise such objects in structural terms.
French, Steven
core
Multi‐institutional study on image quality for a novel CBCT solution on O‐ring linac
Abstract Introduction This work presents a multi‐institutional study on image quality provided by a novel cone beam computed tomography (CBCT). The main goal is to investigate the consistency of imaging performance across multiple institutions.
Luis Agulles‐Pedrós+11 more
wiley +1 more source