Results 51 to 60 of about 2,043,284 (342)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Conservation Laws and Traveling Wave Solutions of a Generalized Nonlinear ZK-BBM Equation
Abstract and Applied Analysis, 2014 We study a generalized two-dimensional nonlinear Zakharov-Kuznetsov-Benjamin-Bona-Mahony (ZK-BBM) equation, which is in fact Benjamin-Bona-Mahony equation formulated in the ZK sense.
Khadijo Rashid Adem +1 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Abstract and Applied Analysis, 2014 We study two nonlinear partial differential equations, namely, the symmetric regularized long wave equation and the Klein-Gordon-Zakharov equations. The Lie symmetry approach along with the simplest equation and exp-function methods are used to obtain ...
Isaiah Elvis Mhlanga +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Open Physics, 2018 In this paper, we study a (2+1) dimensional KdV-mKdV equation, which models many physical phenomena of mathematical physics. This equation has two integral terms in it.
Motsepa Tanki, Masood Khalique Chaudry
doaj +1 more source
Spin-Flavour Symmetry and Contractions Towards Classical Space-Time Symmetry [PDF]
, 1996 A classification scheme of hadrons is proposed on the basis of the division algebra H of quaternions and an appropriate geometry. This scheme suggests strongly to understand flavour symmetry in another manner than from standard symmetry schemes.
Dahm, Rolf
core +2 more sources
Symmetry of system and system of symmetry
Computers & Mathematics with Applications, 1986 AbstractRelation “symmetry-system” is investigated from the point of view of the author's version of general systems theory (GST(U)). The symmetry of system is explicated in three ways: (i) in the form of the theory of groups of nonevolutionary and evolutionary system transformations and their invariants, (ii) in the form of a proof of symmetry of the ...
openaire +2 more sources
FEBS Open Bio, EarlyView.d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada +3 more
wiley +1 more source
Faddeev-type equations for three-body symmetry violating scattering amplitudes [PDF]
, 2010 The equations which relate three-body and two-body symmetry violating scattering amplitudes are derived in the first order of symmetry violating interactions.
L. D. Faddeev +3 more
core +3 more sources