Results 51 to 60 of about 10,042,261 (306)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Physics Letters BWe study a higher group analog of the Weyl symmetry in four-dimensional quantum field theories. A typical example is that the modified transformation of the 2-form background gauge field replaces the operator-valued Weyl anomaly associated with gauging ...
Yu Nakayama
doaj +1 more source
Person Re-Identification via Group Symmetry Theory
IEEE Access, 2019 In recent years, deep learning represented by convolutional neural networks (CNNs) has developed rapidly. The development of deep learning has also led to rapid progress in the field of person re-identification. Many related researchers have begun to use
Jiahuan Zhang +5 more
doaj +1 more source
Automorphic Lie algebras with dihedral symmetry [PDF]
, 2014 The concept of automorphic Lie algebras arises in the context of reduction groups introduced in the early 1980s in the field of integrable systems.
Sanders, Jan +9 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Symmetry in Signals: A New Insight
EntropySymmetry is a fundamental property of many natural systems, which is observable through signals. In most out-of-equilibrium complex dynamic systems, the observed signals are asymmetric. However, for certain operating modes, some systems have demonstrated
Jean-Marc Girault
doaj +1 more source
Constraints on 3- and 4-loop β-functions in a general four-dimensional Quantum Field Theory
Journal of High Energy Physics, 2019 The β-functions of marginal couplings are known to be closely related to the A-function through Osborn’s equation, derived using the local renormalization group. It is possible to derive strong constraints on the β-functions by parametrizing the terms in
Colin Poole, Anders Eller Thomsen
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Symmetry and group theory throughout physics
EPJ Web of Conferences, 2012 As noticed in 1884 by Pierre Curie [1], physical properties of matter are tightly related to the kind of symmetry of the medium. Group theory is a systematic tool, though not always easy to handle, to exploit symmetry properties, for instance to find the
Villain J.
doaj +1 more source