Comprehensive mapping of sensory and sympathetic innervation of the developing kidney [PDF]
Summary: The kidneys act as finely tuned sensors to maintain physiological homeostasis. Both sympathetic and sensory nerves modulate kidney function through precise neural control.
Rose Z Hill, Lori L O'brien
exaly +4 more sources
Heterogeneous cardiac sympathetic innervation gradients promote arrhythmogenesis in murine dilated cardiomyopathy [PDF]
Ventricular arrhythmias (VAs) in heart failure are enhanced by sympathoexcitation. However, radiotracer studies of catecholamine uptake in failing human hearts demonstrate a proclivity for VAs in patients with reduced cardiac sympathetic innervation.
Al-Hassan J. Dajani +17 more
doaj +2 more sources
Sympathetic nerve-derived ATP regulates renal medullary blood flow via vasa recta pericytes [PDF]
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa
Scott S Wildman
doaj +4 more sources
Sympathetic innervation of human and porcine spleens: implications for between species variation in function [PDF]
Background The vagus nerve affects innate immune responses by activating spleen-projecting sympathetic neurons, which modulate leukocyte function. Recent basic and clinical research investigating vagus nerve stimulation to engage the cholinergic anti ...
Logan G. Kirkland +6 more
doaj +2 more sources
Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue [PDF]
Summary: Sympathetic innervation of brown adipose tissue (BAT) controls mammalian adaptative thermogenesis. However, the cellular and molecular underpinnings contributing to BAT innervation remain poorly defined.
Derek Lee +7 more
doaj +2 more sources
High-resolution imaging atlas reveals the context-dependent role of pancreatic sympathetic innervation in diabetic mice [PDF]
A better understanding of how sympathetic nerves impact pancreatic function is helpful for understanding diabetes. However, there is still uncertainty and controversy surrounding the roles of sympathetic nerves within the pancreas.
Xu Qingqing +12 more
doaj +2 more sources
Sympathetic innervation of human muscle spindles [PDF]
AbstractThe aim of the present study was to investigate the presence of sympathetic innervation in human muscle spindles, using antibodies against neuropeptide Y (NPY),NPYreceptors and tyrosine hydroxylase (TH). A total of 232 muscle spindles were immunohistochemically examined.NPYandNPYreceptors were found on the intrafusal fibers, on the blood ...
Kevin Peikert, Mona Lindström
exaly +4 more sources
Islet sympathetic innervation and islet neuropathology in patients with type 1 diabetes [PDF]
Dysregulation of glucagon secretion in type 1 diabetes (T1D) involves hypersecretion during postprandial states, but insufficient secretion during hypoglycemia. The sympathetic nervous system regulates glucagon secretion. To investigate islet sympathetic
Martha Campbell-Thompson +11 more
doaj +2 more sources
Myocardial Sympathetic Innervation Imaging [PDF]
Peacock, Justin G., Farrell, Mary Beth
openaire +3 more sources
Sympathetic neuropathology is revealed in muscles affected by amyotrophic lateral sclerosis
Rationale: The anatomical substrate of skeletal muscle autonomic innervation has remained underappreciated since it was described many decades ago. As such, the structural and functional features of muscle sympathetic innervation are largely undetermined
Antonio Mazzaro +18 more
doaj +1 more source

