Results 21 to 30 of about 53,521 (302)

Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration.

PLoS ONE, 2020
Cardiac dysautonomia is a common nonmotor symptom of Parkinson's disease (PD) associated with loss of sympathetic innervation to the heart and decreased plasma catecholamines.
Jeanette M Metzger, Helen N Matsoff, Alexandra D Zinnen, Rachel A Fleddermann, Viktoriya Bondarenko, Heather A Simmons, Andres Mejia, Colleen F Moore, Marina E Emborg   +8 more
doaj   +1 more source

Autonomic innervation of the cardio-vascular system in normal tension glaucoma patients

Oftalʹmologiâ, 2014
Purpose: to determine whether there is any difference in autonomic innervation of the cardio-vascular system in normal tension glaucoma (NtG) patients and primary open angle glaucoma (POAG) patients.Methods: 30 NtG patients, 30 POAG patients and 22 ...
N. I. Kurysheva, V. N. Trubilin, M. A. Tsaregorodtseva, T. Ya. Ryabova, V. N. Shlapak, E. Yu. Irtegova   +5 more
doaj   +3 more sources

Preganglionic innervation of the pancreas islet cells in the rat [PDF]

, 1984
The position and number of preganglionic somata innervating the insulin-secreting β-cells of the endocrine pancreas were investigated in Wistar rats.
Horst, G.J. ter,, Koopmans, S.J.,, Luiten, P.G.M.,, Rietberg, M.,, Steffens, A.B.,   +4 more
core   +2 more sources

Small Fiber Polyneuropathy May Be a Nexus Between Autonomic Nervous System Dysregulation and Pain in Interstitial Cystitis/Bladder Pain Syndrome

Frontiers in Pain Research, 2022
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a highly heterogeneous chronic and debilitating condition which effects millions of women and men in the United States. While primarily defined by urinary symptoms and pain perceived to be emanating
Dylan T. Wolff, Stephen J. Walker, Stephen J. Walker   +2 more
doaj   +1 more source

Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation [PDF]

, 2016
Background Nerve growth factor (NGF) is the prototypical target-derived neurotrophic factor required for sympathetic neuron survival and for the growth and ramification of sympathetic axons within most but not all sympathetic targets.
Davies, Alun M., Gavaldà, Núria, Gutierrez, Humberto, Howard, Laura, Laurie, Christopher W., Osorio, Catarina, O’Keeffe, Gerard W., Wyatt, Sean L.   +7 more
core   +2 more sources

Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis

Molecular Metabolism, 2018
Objective: Crosstalk between adipocytes and local neurons may be an important regulatory mechanism to control energy homeostasis. We previously reported that perturbation of adipocyte de novo lipogenesis (DNL) by deletion of fatty acid synthase (FASN ...
Adilson Guilherme, David J. Pedersen, Felipe Henriques, Alexander H. Bedard, Elizabeth Henchey, Mark Kelly, Donald A. Morgan, Kamal Rahmouni, Michael P. Czech   +8 more
doaj   +1 more source

Age-Related Variation in Sympathetic Nerve Distribution in the Human Spleen

Frontiers in Neuroscience, 2021
Introduction: The cholinergic anti-inflammatory pathway (CAIP) has been proposed as an efferent neural pathway dampening the systemic inflammatory response via the spleen.
Cindy G. J. Cleypool, David J. Brinkman, David J. Brinkman, Claire Mackaaij, Peter G. J. Nikkels, Martijn A. Nolte, Misha D. Luyer, Wouter J. de Jonge, Wouter J. de Jonge, Ronald L. A. W. Bleys   +9 more
doaj   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Loss of Sympathetic Nerves in Spleens from Patients with End Stage Sepsis

Frontiers in Immunology, 2017
The spleen is an important site for central regulation of immune function by noradrenergic sympathetic nerves, but little is known about this major region of neuroimmune communication in humans.
Donald B. Hoover, Donald B. Hoover, Thomas Christopher Brown, Madeleine K. Miller, John B. Schweitzer, John B. Schweitzer, David L. Williams, David L. Williams   +7 more
doaj   +1 more source

The sources of innervation of the aortic arch and thoracic aorta in human fetuses [PDF]

Archives of the Balkan Medical Union, 2021
Introduction. The development of angiosurgery requires the morphologists to clarify in more details the topographic anatomical peculiarities of arterial vessels, considering their morphogenesis, peculiarities of innervation, age and individual anatomical
Galyna Ya. STELMAKH, Tatiana V. KHMARA, Inna V. LUKASHEVYCH, Volodymyr V. VIZNIUK, Iryna D. KIIUN, Ruslan P. KNUT   +5 more
doaj   +1 more source