Results 21 to 30 of about 6,210,925 (258)

Advances in sympathetic nerve recording in humans

open access: yesFrontiers in Physiology, 2012
Sympathetic nerve recording is commonly assessed by measuring the firing activity of a number of neurones. While the estimation of overall sympathetic nervous activity using this multiunit recording approach has advanced our understanding of sympathetic ...
Elisabeth eLambert   +7 more
doaj   +1 more source

PACAP-PAC1 Receptor Activation Is Necessary for the Sympathetic Response to Acute Intermittent Hypoxia

open access: yesFrontiers in Neuroscience, 2019
Repetitive hypoxia is a key feature of obstructive sleep apnoea (OSA), a condition characterized by intermittent airways obstruction. Patients with OSA present with persistent increases in sympathetic activity and commonly develop hypertension.
Melissa M. J. Farnham   +17 more
doaj   +1 more source

Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis

open access: yesNature Communications, 2019
Bone is innervated, and its turnover is affected by sympathetic nerve activity. Here, the authors show that prostaglandin E2, secreted by osteoblasts, activates the EP4 receptor on sensory nerves, inhibiting sympathetic nerve activity and modulating bone
Hao Chen   +21 more
doaj   +1 more source

Mapping the cellular electrophysiology of rat sympathetic preganglionic neurones to their roles in cardiorespiratory reflex integration:A whole cell recording study in situ [PDF]

open access: yes, 2014
Sympathetic preganglionic neurones (SPNs) convey sympathetic activity flowing from the CNS to the periphery to reach the target organs. Although previous in vivo and in vitro cell recording studies have explored their electrophysiological characteristics,
Briant, Linford J B   +7 more
core   +1 more source

Functional-Optical Coherence Tomography: A Non-invasive Approach to Assess the Sympathetic Nervous System and Intrinsic Vascular Regulation

open access: yesFrontiers in Physiology, 2019
Sympathetic nervous system dysregulation and vascular impairment in neuronal tissue beds are hallmarks of prominent cardiorespiratory diseases. However, an accurate and convenient method of assessing SNA and local vascular regulation is lacking ...
Nicholas G. Jendzjowsky   +8 more
doaj   +1 more source

Sympathetic neural control of integrated cardiovascular function: Insights from measurement of human sympathetic nerve activity

open access: yes, 2007
Sympathetic neural control of cardiovascular function is essential for normal regulation of blood pressure and tissue perfusion. In the present review we discuss sympathetic neural mechanisms in human cardiovascular physiology and pathophysiology, with a
B. Gunnar Wallin   +3 more
core   +1 more source

Hepatoportal Leptin Sensors and Their Reflex Effects on Autonomic Outflow in the Rat

open access: yesJournal of Obesity, 2011
Afferent nerve signals were recorded from a peripheral cut end of the small nerve bundle of the hepatic branch of the vagus nerve in anesthetized rats. An injection of leptin (100 pg, 0.1 mL) into the portal vein facilitated the afferent activity.
Akira Niijima
doaj   +1 more source

Real-time imaging of the medullary circuitry involved in the generation of spontaneous muscle sympathetic nerve activity in awake human subjects [PDF]

open access: yes, 2008
In order to understand the central neural processes involved in blood pressure regulation we recorded muscle sympathetic nerve activity (MSNA) via a tungsten microelectrode in the common peroneal nerve while performing functional Magnetic Resonance ...
Vaughan Macefield, Luke Henderson
core  

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Effects of L- and N-Type Ca Channel Blocker Cilnidipine on Changes in Heart Rate and QT Interval During Dialysis

open access: yesKidney & Blood Pressure Research, 2017
Background/Aims: Hemodialysis patients have poor prognosis due to increased prevalence of cardiovascular diseases. Treatment to suppress increases in sympathetic nerve activity and QT prolongation may have the potential to reduce the occurrence of these ...
Takeshi Iida   +4 more
doaj   +1 more source

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