Results 41 to 50 of about 6,210,925 (258)

Efficacy of the lumbar sympathetic ganglion block in lower limb pain and its application prospects during the perioperative period

Ibrain, 2022
The sympathetic nervous system is involved in the physiological pathogenesis of many different types of chronic pain. Sympathetic blocks can interrupt the reflex control system by intercepting the noxious afferent fibers accompanying autonomic nerves ...
Jing‐Han Zhang, Yan‐Ping Deng, Min‐Jian Geng   +2 more
doaj   +1 more source

Modulation of Synaptic Amplification in Sympathetic Ganglia [PDF]

, 2013
The purpose of this dissertation was to assess synaptic integration in neurons from the rat superior cervical ganglion (SCG) using complex temporal patterns of virtual synaptic activity that mimic in vivo conditions.
Springer, Mitchell
core  

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

Nitric oxide mediates the blood pressure response to mental stress in humans

Swiss Medical Weekly, 2012
OBJECTIVE: Nitric oxide (NO) regulates arterial pressure by modulating peripheral vascular tone and sympathetic vasoconstrictor outflow. NO synthesis is impaired in several major cardiovascular disease states.
Lionel Trueb, Mattia Lepori, Hervé Duplain, Urs Scherrer, Claudio Sartori   +4 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Highly localized interactions between sensory neurons and sprouting sympathetic fibers observed in a transgenic tyrosine hydroxylase reporter mouse

Molecular Pain, 2011
Background Sprouting of sympathetic fibers into sensory ganglia occurs in many preclinical pain models, providing a possible anatomical substrate for sympathetically enhanced pain.
Zhang Jun-Ming, Mao Juxian, Strong Judith A, Xie Wenrui   +3 more
doaj   +1 more source

Baseline sympathetic nerve activity.

, 2016
(A) Splanchnic sympathetic nerve activity (sSNA, n = 9) and (B) renal sympathetic nerve activity (rSNA, n = 9) at baseline level in the different groups. BDL, bile duct ligation. Error bars indicate SEM.
Heder F. G. Estrela (2602684), Ruy R. Campos (479513), Cássia T. Bergamaschi (2602687), Elaine S. Damásio (2602690), Eduardo K. U. N. Fonseca (2602681)   +4 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

TLR4 participates in sympathetic hyperactivity Post-MI in the PVN by regulating NF-κB pathway and ROS production

Redox Biology, 2019
Sympathetic nerve hyperactivity is a primary reason for fatal ventricular arrhythmias (VAs) following myocardial infarction (MI). Pro-inflammatory cytokines produced in the paraventricular nucleus (PVN) post-MI are associated with sympathetic ...
Yu Wang, Hesheng Hu, Jie Yin, Yugen Shi, Jiayu Tan, Lu Zheng, Cailing Wang, Xiaolu Li, Mei Xue, Ju Liu, Ye Wang, Yan Li, Xinran Li, Fuhong Liu, Qiang Liu, Suhua Yan   +15 more
doaj   +1 more source

Immersion of the hand in ice water releases adrenergic vasoconstrictor tone in the ipsilateral temple [PDF]

, 2006
Immersion of the hand in painfully cold water induces cutaneous vasodilatation in the temples, more so ipsilaterally than contralaterally. To investigate the mechanism of this response, guanethidine or saline was administered by transcutaneous ...
Drummond, P.D.
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