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The Sympathetic Nervous System in Hypertension
2018It has been clearly shown that adrenergic tone has a primary role in blood pressure control due to the regulatory effects on cardiac output and systemic vascular resistance. Several mechanisms, both at central and peripheral levels, participate in this control exerted by the sympathetic nervous system.
Seravalle G., Mancia G., Grassi G.
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Antihypertensive Drugs and the Sympathetic Nervous System
Journal of Cardiovascular Pharmacology, 2007Hypertension has been associated with several modifications in the function and regulation of the sympathetic nervous system (SNS). Although it is unclear whether this dysfunction is primary or secondary to the development of hypertension, these alterations are considered to play an important role in the evolution, maintenance, and development of ...
DEL COLLE S +7 more
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Immunoregulation mediated by the sympathetic nervous system, II
Cellular Immunology, 1979Abstract The effect of acute immunization or continuous environmental antigenic exposure on nor-adrenaline (NA) content of rat lymphoid organs was studied. Immunization with sheep red blood cells resulted in a decrease in splenic NA content. In other experiments, NA levels were determined in lymphoid and nonlymphoid organs of SPF rats exposed to ...
Besedovsky, H O +4 more
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The sympathetic nervous system and the metabolic syndrome
Journal of Hypertension, 2007Studies performed in the past two decades have unequivocally shown that several of the components of the metabolic syndrome are associated with indirect and direct markers of adrenergic overdrive. This is the case for hypertension and obesity, in which resting tachycardia, elevated plasma norepinephrine values, increased sympathetic nerve traffic, as ...
MANCIA, GIUSEPPE +7 more
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Sympathetic Nervous System, Sleep, and Hypertension
Current Hypertension Reports, 2018To evaluate the relation between sleep alterations, with or without breathing disorders, and incidence of hypertension and other cardiovascular diseases RECENT FINDINGS: Several studies have clearly shown the mechanisms linking sleep disorders and cardiovascular diseases.
Seravalle, G, Mancia, G, Grassi, G
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Sympathetic Nervous System and Hypertension
1974The role of the sympathetic nervous system in the pathogenesis of essential human hypertension is not yet established [6, 7, 10, 11, 25, 36]. In spite of this the majority of drugs currently used in the treatment of human hypertension act by modifying peripheral and/or central adrenergic mechanisms [27].
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Tumours of the Sympathetic Nervous System
1975Neuroblastomas, ganglioneuromas and phaeochromocytomas are the three tumours of the sympathetic nervous system which arise from the same tissue in embryonic life and have the same anatomical sites. They vary in pathological anatomy but are similar in biochemistry. They differ in symptoms, diagnosis and therapy.
W. J. van Putten +2 more
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Essential hypertension and the sympathetic nervous system
Neurological Sciences, 2008Sympathetic neural factors exert a key role in homeostatic blood pressure control. Evidence is available that abnormalities in sympathetic function may favour the development and progression of the hypertensive state. This paper will review the data collected throughout the years on the role of adrenergic mechanisms in the pathophysiology of the ...
GRASSI, GUIDO +3 more
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The central sympathetic nervous system in hypertension
2013The sympathetic nervous system participates in the development and progression of the essential hypertensive state, as shown by increased circulating plasma levels of the adrenergic neurotransmitter norepinephrine, elevated norepinephrine spillover rate, and augmented sympathetic nerve traffic discharge detected in the high blood pressure state.
Mancia, G, Grassi, G
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The Sympathetic Nervous System
2000Altered function of the sympathetic nervous system (SNS), whether caused by age per se or by age-associated disease, may contribute to impaired homeostasis in aging. The SNS occupies a central role in the maintenance of homeostasis because of its involvement in the regulation of many important physiologic functions.
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