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The sympathetic nervous system and the metabolic syndrome
Journal of Hypertension, 2007Studies performed in the past two decades have unequivocally shown that several of the components of the metabolic syndrome are associated with indirect and direct markers of adrenergic overdrive. This is the case for hypertension and obesity, in which resting tachycardia, elevated plasma norepinephrine values, increased sympathetic nerve traffic, as ...
MANCIA, GIUSEPPE +7 more
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Sympathetic Nervous System, Sleep, and Hypertension
Current Hypertension Reports, 2018To evaluate the relation between sleep alterations, with or without breathing disorders, and incidence of hypertension and other cardiovascular diseases RECENT FINDINGS: Several studies have clearly shown the mechanisms linking sleep disorders and cardiovascular diseases.
Seravalle, G, Mancia, G, Grassi, G
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Essential hypertension and the sympathetic nervous system
Neurological Sciences, 2008Sympathetic neural factors exert a key role in homeostatic blood pressure control. Evidence is available that abnormalities in sympathetic function may favour the development and progression of the hypertensive state. This paper will review the data collected throughout the years on the role of adrenergic mechanisms in the pathophysiology of the ...
GRASSI, GUIDO +3 more
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Sympathetic Nervous System and Hypertension
1974The role of the sympathetic nervous system in the pathogenesis of essential human hypertension is not yet established [6, 7, 10, 11, 25, 36]. In spite of this the majority of drugs currently used in the treatment of human hypertension act by modifying peripheral and/or central adrenergic mechanisms [27].
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Tumours of the Sympathetic Nervous System
1975Neuroblastomas, ganglioneuromas and phaeochromocytomas are the three tumours of the sympathetic nervous system which arise from the same tissue in embryonic life and have the same anatomical sites. They vary in pathological anatomy but are similar in biochemistry. They differ in symptoms, diagnosis and therapy.
W. J. van Putten +2 more
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The central sympathetic nervous system in hypertension
2013The sympathetic nervous system participates in the development and progression of the essential hypertensive state, as shown by increased circulating plasma levels of the adrenergic neurotransmitter norepinephrine, elevated norepinephrine spillover rate, and augmented sympathetic nerve traffic discharge detected in the high blood pressure state.
Mancia, G, Grassi, G
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The Sympathetic Nervous System
2000Altered function of the sympathetic nervous system (SNS), whether caused by age per se or by age-associated disease, may contribute to impaired homeostasis in aging. The SNS occupies a central role in the maintenance of homeostasis because of its involvement in the regulation of many important physiologic functions.
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Sympathetic nervous system and metabolism [PDF]
, 1999 At the outset it is important to define the elements of the sympathetic nervous system (SNS) that are involved in the response to critical illness; for example, endocrine responses to adrenaline (A) compared to local neurotransmitter release, i.e. noradrenaline (NA) in pancreas, skeletal muscle, liver, etc. It must also be remembered that activation of
G. L. Carlson, Roderick A. Little
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Sympathetic nervous system and the kidney in hypertension
Current Opinion in Nephrology and Hypertension, 2002Long-term control of arterial pressure has been attributed to the kidney by virtue of its ability to couple the regulation of blood volume to the maintenance of sodium and water balance by the mechanisms of pressure natriuresis and diuresis. In the presence of a defect in renal excretory function, hypertension arises as the consequence of the need for ...
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Pharmacology of the sympathetic nervous system
1966Drugs may interfere with the efferent sympathetic system, mainly at four different levels: 1) the sympathetic centres (and these in turn are located at different levels), 2) the sympathetic ganglia, 3) the postganglionic sympathetic nerve-endings, and 4) the effector cells (smooth muscle, heart, glands, etc.). In general their actions are brought about
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