Results 91 to 100 of about 9,122 (283)

The thoracic perivascular adipose tissue spontaneously induces vasoconstriction through activation of α1‐adrenoceptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4535-4552, October 2025.
Background and Purpose Although perivascular adipose tissue (PVAT) contains substances with contractile properties, its actions on the vascular tone are associated with the release of anticontractile substances. We hypothesize that procontractile PVAT products also exert direct effects on vascular tone. Experimental Approach Thoracic aortas from Wistar
Leonardo Gomes‐Pereira   +1 more
wiley   +1 more source

Dexmedetomidine Protects against Ischemia and Reperfusion-Induced Kidney Injury in Rats

open access: yesMediators of Inflammation, 2020
Acute kidney injury (AKI), a clinical syndrome, is a sudden onset of kidney failure that severely affects the kidney tubules. One potential treatment is dexmedetomidine (DEX), a highly selective α2-adrenoreceptor agonist that is used as an anesthetic ...
Naren Bao, Di Dai
doaj   +1 more source

Iatrogenic pulsus alternans in a dog undergoing median sternotomy

open access: yesVeterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract A 6‐year‐old, 21.8 kg, female, spayed Siberian husky was referred for management of a spontaneous bilateral pneumothorax, due to a ruptured pulmonary bleb. During surgery, sterile saline was instilled on three occasions in order to locate the damaged lung tissue and ensure complete ligation.
Marie‐Line Doï   +2 more
wiley   +1 more source

Analgesic efficacy of stellate ganglion block in head and neck cancer pain: A case series

open access: yesJournal of Family Medicine and Primary Care
Patients with head and neck cancer (HNC) have ongoing pain but Stellate ganglion block which is a sympatholytic block may be a viable therapy for treating it.
Seerat Chiraya   +3 more
doaj   +1 more source

Benefits of using dexmedetomidine during carotid endarterectomy: A review

open access: yesSaudi Journal of Anaesthesia, 2014
As per current recommendation, patients with acute ischemic stroke should be offered carotid endarterectomy (CEA) within 24-72 hours. The same applies to patients with recurrent transient ischemic attacks (TIA).
Abhijit S Nair
doaj   +1 more source

Experimental gastric ulcers induced by immobilization and electric shock of rats and their pharmacotherapy [PDF]

open access: yes
The mechanism of development of experimental gastric ulcers, induced in rats by combined immobilization and electric shock, was analyzed pharmacologically with peripheral neurotropic agents.
Zabrodin, O. N.
core   +1 more source

Thoracic Epidural Anesthesia Can Be Effective for the Short‐Term Management of Ventricular Tachycardia Storm [PDF]

open access: yes, 2017
Background Novel therapies aimed at modulating the autonomic nervous system, including thoracic epidural anesthesia (TEA), have been shown in small case series to be beneficial in treating medically refractory ventricular tachycardia (VT) storm. However,
Ajijola Olujimi A.   +10 more
core   +2 more sources

Efficacy and Safety of Lorundrostat in Uncontrolled Hypertension: A Systematic Review and Meta‐Analysis

open access: yesThe Journal of Clinical Hypertension, Volume 27, Issue 9, September 2025.
Abstract This systematic review and meta‐analysis evaluated the efficacy and safety of lorundrostat in adults with uncontrolled hypertension. Following PRISMA guidelines and PROSPERO registration (CRD420251088503), five databases were systematically searched through July 2025 for randomized controlled trials comparing lorundrostat with placebo in this ...
Allah Dad   +14 more
wiley   +1 more source

A case report of clonidine induced syncope: a review of central actions of an old cardiovascular drug

open access: yesBMC Pharmacology and Toxicology, 2018
Background Clonidine is an imidazoline sympatholytic, acting on both α2-adrenergic and imidazoline receptors in the brainstem to induce antihypertensive and negative chronotropic effects in the vasculature and heart respectively.
Alexander J. Sandweiss   +3 more
doaj   +1 more source

Ulcers in restrained rats: Study of protective substances [PDF]

open access: yes
The genesis of ulcers in restrained rats is discussed through an investigation of the relationship between the protective effects of nervous system effectual substances examined vis-a-vis ulcers in restrained rats and their elective or secondary ...
Buche, L., Gallaire, D.
core   +1 more source

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