Micro-RNAS that control myosin expression and myofiber identity [PDF]
The present invention relates to the identification of two microRNAs, miR-499 and miR-208b, that repress fast skeletal muscle contractile protein genes. Expression of miR-499 and/or miR-208b can be used to repress fast fiber genes and activate slow fiber
Olson, Eric N., van Rooij, Eva
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Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex [PDF]
Rationale: Pupillometry can be used to characterize autonomic drug effects. Objective: This study was conducted to determine the autonomic effects of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy), administered alone and after pretreatment with ...
Hysek, Cédric, Liechti, Matthias
core
Body Condition and the Adrenal Stress Response in Captive American Kestrel Juveniles [PDF]
We examined the adrenal response to handling stress of birds in different body conditions. In order to affect the birds’ body condition, young (73-d old) female American kestrels (Falco sparverius) were maintained for 6 wk on one of three diets: a ...
Dufty, Alfred M., Jr., Heath, Julie A.
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ADRENOLYTIC AND SYMPATHOLYTIC PROPERTIES OF 2‐HALOGENOALKYLAMINES IN THE VAS DEFERENS OF THE GUINEA‐PIG [PDF]
John D. Graham, Husam Katib
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Comparison of the eficacy and safety of 4 mg of ondansetron vs. 4 mg of nalbuphine for the treatment of neuraxial morphineinduced pruritus [PDF]
Objective: To compare the eficacy and safety of 4 mg of ondansetron vs. 4 mg of nalbuphine for the treatment of neuraxial morphine-induced pruritus, in patients at the “Dr.
Cano García, Martha Araceli +6 more
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THE USE OF THE RAT'S ISOLATED SEMINAL VESICLE FOR THE ASSAY OF SYMPATHOLYTIC DRUGS* [PDF]
James L. Leitch +2 more
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• Central sympatholytic drugs reduce blood pressure mainly by stimulating central α(2) -adrenergic receptors in the brainstem centers, thereby reducing sympathetic nerve activity and neuronal release of norepinephrine to the heart and peripheral circulation.
Wanpen, Vongpatanasin +3 more
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Angiotensin receptor-1 antagonist eprosartan in patients with mild to moderate arterial hypertension
Aim. To study clinical effectiveness of eprosartan mesylate in treating patients with Stage I-II arterial hypertension (AH). Material and methods. In total, 28 patients (20 males, 8 females) with Stage I-II AH, risk 2-3, aged 28-56 years (mean age 40.0±1.
A. V. Shabalin +2 more
doaj
Progress on the Mechanisms and Neuroprotective Benefits of Dexmedetomidine in Brain Diseases
Introduction Dexmedetomidine, a highly specific α2 agonist, has been extensively utilized in clinical sedation and surgical anesthesia since its introduction in 2000 due to its excellent sympatholytic, sedative, and analgesic effects.
Zhenxing Tao, Pengpeng Li, Xudong Zhao
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