Results 11 to 20 of about 1,690 (172)

Pediatric clonidine and guanfacine poisoning: a single-center retrospective review

Toxicology Communications, 2021
Clonidine and guanfacine are centrally acting sympatholytics (CAS). Poisoning with these agents is common in children, and management of this poisoning is controversial. We sought to characterize our experience with pediatric CAS poisonings.
Kevin Baumgartner, Michael Mullins
doaj   +1 more source

Place of imidazoline receptor agonists in the treatment of arterial hypertension

Рациональная фармакотерапия в кардиологии, 2023
The review is devoted to one of the most controversial issues of modern antihypertensive therapy — the role of new generation sympatholytics — selective I1-imidazoline receptor agonists (AIRs).
D. V. Nebieridze, A. S. Safaryan, E. I. Ivanova, E. A. Poddubskaya   +3 more
doaj   +1 more source

Sympatholytic Mechanisms for the Beneficial Cardiovascular Effects of SGLT2 Inhibitors: A Research Hypothesis for Dapagliflozin's Effects in the Adrenal Gland. [PDF]

Int J Mol Sci, 2021
Lymperopoulos A, Borges JI, Cora N, Sizova A.   +3 more
europepmc   +3 more sources

Anesthesia and Cancer, Friend or Foe? A Narrative Review

Frontiers in Oncology, 2021
Cancer remains the leading cause of death worldwide with close to 10 million deaths reported annually. Due to growth of the advanced age cohort in our population, it is predicted that the number of new cancer cases diagnosed between now until 2035 is to ...
Julio Montejano, Vesna Jevtovic-Todorovic   +1 more
doaj   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document. [PDF]

Eur J Heart Fail
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Abdin A, Bauersachs J, Abdelhamid M, Aktaa S, Al Ghorani H, Bayes-Genis A, Biegus J, Böhm M, Butler J, Girerd N, Metra M, Mullens W, Skouri H, Vaduganathan M, El Hadidi S, Rosano GMC, Savarese G.   +16 more
europepmc   +2 more sources

Efficacy and Safety of Lorundrostat in Uncontrolled Hypertension: A Systematic Review and Meta-Analysis. [PDF]

J Clin Hypertens (Greenwich)
Abstract This systematic review and meta‐analysis evaluated the efficacy and safety of lorundrostat in adults with uncontrolled hypertension. Following PRISMA guidelines and PROSPERO registration (CRD420251088503), five databases were systematically searched through July 2025 for randomized controlled trials comparing lorundrostat with placebo in this ...
Dad A, Bakht K, Tahir HB, Arham M, Goel A, Ahmad MM, Raza S, Qadri SH, Rathi D, Javed S, Hamdani SSQ, Arshad H, Abubakar FNU, Awais MN, Nizam MA.   +14 more
europepmc   +2 more sources

Evaluation of Nebulised Dexmedetomidine in Blunting Haemodynamic Response to Laryngoscopy and Intubation in Adults Undergoing General Anaesthesia for Laparoscopic Surgeries: A Randomised Control Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Laryngoscopy and endotracheal intubation can trigger sympathetic stimulation, potentially leading to cardiovascular or cerebrovascular complications in high-risk patients.
Et Muhammed Jaseel, Shweta Sedani, Dipakkumar Hiralal Ruparel, Ramesh Sugandh   +3 more
doaj   +1 more source

Does moxonidine reduce Achilles tendon or musculoskeletal pain in women with polycystic ovarian syndrome? A secondary analysis of a randomised controlled trial

BMC Endocrine Disorders, 2020
Background Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive and was therefore an appropriate ...
Jacob Jewson, Elisabeth Lambert, Carolina Sari, Eveline Jona, Soulmaz Shorakae, Gavin Lambert, Jamie Gaida   +6 more
doaj   +1 more source

Characteristics, Management, and Outcomes of Hospitalized Patients with Orthostatic Hypotension. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT Orthostatic hypotension (OH) is a common inpatient condition associated with falls, syncope, and mortality. However, standardized approaches for inpatient management of OH are lacking and may vary across clinical specialties. In this retrospective observational cohort study, we reviewed the electronic medical records of patients admitted to ...
Wagner BA, Rose E, Strauss AC, Khan S, Anderson TS, Juraschek SP.   +5 more
europepmc   +2 more sources

Отечественный и зарубежный опыт применения препарата Физиотенз® в лечении «заболеваний цивилизации»

Архивъ внутренней медицины, 2012
The article summarizes facilities of moxonidine (Physiotens®) — currently one of the most commonly used antihypertensive medicine from sympatholytics. In addition to effects on blood pressure, we provide data on the effects of moxonidine (Physiotens®) on
А. А. Михайлов, А. М. Шилов, А. А. Спасский   +2 more
doaj   +1 more source