Results 11 to 20 of about 1,482 (172)

Place of imidazoline receptor agonists in the treatment of arterial hypertension

Рациональная фармакотерапия в кардиологии, 2023
The review is devoted to one of the most controversial issues of modern antihypertensive therapy — the role of new generation sympatholytics — selective I1-imidazoline receptor agonists (AIRs).
D. V. Nebieridze, A. S. Safaryan, E. I. Ivanova, E. A. Poddubskaya   +3 more
doaj   +1 more source

Anesthesia and Cancer, Friend or Foe? A Narrative Review

Frontiers in Oncology, 2021
Cancer remains the leading cause of death worldwide with close to 10 million deaths reported annually. Due to growth of the advanced age cohort in our population, it is predicted that the number of new cancer cases diagnosed between now until 2035 is to ...
Julio Montejano, Vesna Jevtovic-Todorovic   +1 more
doaj   +1 more source

Evaluation of Nebulised Dexmedetomidine in Blunting Haemodynamic Response to Laryngoscopy and Intubation in Adults Undergoing General Anaesthesia for Laparoscopic Surgeries: A Randomised Control Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Laryngoscopy and endotracheal intubation can trigger sympathetic stimulation, potentially leading to cardiovascular or cerebrovascular complications in high-risk patients.
Et Muhammed Jaseel, Shweta Sedani, Dipakkumar Hiralal Ruparel, Ramesh Sugandh   +3 more
doaj   +1 more source

Does moxonidine reduce Achilles tendon or musculoskeletal pain in women with polycystic ovarian syndrome? A secondary analysis of a randomised controlled trial

BMC Endocrine Disorders, 2020
Background Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive and was therefore an appropriate ...
Jacob Jewson, Elisabeth Lambert, Carolina Sari, Eveline Jona, Soulmaz Shorakae, Gavin Lambert, Jamie Gaida   +6 more
doaj   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document. [PDF]

Eur J Heart Fail
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Abdin A, Bauersachs J, Abdelhamid M, Aktaa S, Al Ghorani H, Bayes-Genis A, Biegus J, Böhm M, Butler J, Girerd N, Metra M, Mullens W, Skouri H, Vaduganathan M, El Hadidi S, Rosano GMC, Savarese G.   +16 more
europepmc   +2 more sources

Отечественный и зарубежный опыт применения препарата Физиотенз® в лечении «заболеваний цивилизации»

Архивъ внутренней медицины, 2012
The article summarizes facilities of moxonidine (Physiotens®) — currently one of the most commonly used antihypertensive medicine from sympatholytics. In addition to effects on blood pressure, we provide data on the effects of moxonidine (Physiotens®) on
А. А. Михайлов, А. М. Шилов, А. А. Спасский   +2 more
doaj   +1 more source

Next Step in Chronic Kidney Disease Therapy

Počki, 2016
Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers are the basis of renoprotection therapy in chronic kidney disease. Parallel to decrease of glomerular filtration rate, there is an increase in the activity of the sympathetic nervous ...
D.D. Ivanov
doaj   +1 more source

Intensive care unit-acquired infection as a side effect of sedation [PDF]

, 2010
Introduction: Sedative and analgesic medications are routinely used in mechanically ventilated patients. The aim of this review is to discus epidemiologic data that suggest a relationship between infection and sedation, to review available data for the ...
Saad Nseir, Demosthenes Makris, Daniel Mathieu, Alain Durocher, Charles-Hugo Marquette   +4 more
core   +1 more source

Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients [PDF]

, 2017
Background: Previous studies have not demonstrated a consistent association between potentially inappropriate medicines (PIMs) in older patients as defined by Beers criteria and avoidable adverse drug events (ADEs).
Byrne, Stephen, Gallagher, Paul F., Hamilton, Hilary J., O'Mahony, Denis, Ryan, Cristin   +4 more
core   +1 more source

Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial [PDF]

, 2010
Introduction Benzodiazepines and α2 adrenoceptor agonists exert opposing effects on innate immunity and mortality in animal models of infection. We hypothesized that sedation with dexmedetomidine (an α2 adrenoceptor agonist), as compared with lorazepam ...
Pratik P Pandharipande, Robert D Sanders, Timothy D Girard, Stuart McGrane, Jennifer L Thompson, Ayumi K Shintani, Daniel L Herr, Mervyn Maze, E Wesley Ely, The MENDS Investigators   +9 more
core   +2 more sources