Results 11 to 20 of about 1,685 (175)

Place of imidazoline receptor agonists in the treatment of arterial hypertension

open access: yesРациональная фармакотерапия в кардиологии, 2023
The review is devoted to one of the most controversial issues of modern antihypertensive therapy — the role of new generation sympatholytics — selective I1-imidazoline receptor agonists (AIRs).
D. V. Nebieridze   +3 more
doaj   +1 more source

Anesthesia and Cancer, Friend or Foe? A Narrative Review

open access: yesFrontiers in Oncology, 2021
Cancer remains the leading cause of death worldwide with close to 10 million deaths reported annually. Due to growth of the advanced age cohort in our population, it is predicted that the number of new cancer cases diagnosed between now until 2035 is to ...
Julio Montejano   +1 more
doaj   +1 more source

Efficacy and Safety of Lorundrostat in Uncontrolled Hypertension: A Systematic Review and Meta-Analysis. [PDF]

open access: yesJ Clin Hypertens (Greenwich)
Abstract This systematic review and meta‐analysis evaluated the efficacy and safety of lorundrostat in adults with uncontrolled hypertension. Following PRISMA guidelines and PROSPERO registration (CRD420251088503), five databases were systematically searched through July 2025 for randomized controlled trials comparing lorundrostat with placebo in this ...
Dad A   +14 more
europepmc   +2 more sources

Does moxonidine reduce Achilles tendon or musculoskeletal pain in women with polycystic ovarian syndrome? A secondary analysis of a randomised controlled trial

open access: yesBMC Endocrine Disorders, 2020
Background Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive and was therefore an appropriate ...
Jacob Jewson   +6 more
doaj   +1 more source

Selection of antihypertensive drugs from the perspective of clinical pharmacology [PDF]

open access: yesThe Moldovan Medical Journal, 2018
Background: The rational use of medicines remains one of the most important directions of public health, especially in socio-medical diseases, including arterial hypertension.
Victor Ghicavii   +4 more
doaj   +1 more source

Characteristics, Management, and Outcomes of Hospitalized Patients with Orthostatic Hypotension. [PDF]

open access: yesJ Clin Hypertens (Greenwich)
ABSTRACT Orthostatic hypotension (OH) is a common inpatient condition associated with falls, syncope, and mortality. However, standardized approaches for inpatient management of OH are lacking and may vary across clinical specialties. In this retrospective observational cohort study, we reviewed the electronic medical records of patients admitted to ...
Wagner BA   +5 more
europepmc   +2 more sources

Отечественный и зарубежный опыт применения препарата Физиотенз® в лечении «заболеваний цивилизации»

open access: yesАрхивъ внутренней медицины, 2012
The article summarizes facilities of moxonidine (Physiotens®) — currently one of the most commonly used antihypertensive medicine from sympatholytics. In addition to effects on blood pressure, we provide data on the effects of moxonidine (Physiotens®) on
А. А. Михайлов   +2 more
doaj   +1 more source

Next Step in Chronic Kidney Disease Therapy

open access: yesPočki, 2016
Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers are the basis of renoprotection therapy in chronic kidney disease. Parallel to decrease of glomerular filtration rate, there is an increase in the activity of the sympathetic nervous ...
D.D. Ivanov
doaj   +1 more source

Tumor necrosis factor, interleukin-1 and interleukin-8 mediate the nociceptive activity of the supernatant of LPS-stimulated macrophages

open access: yesMediators of Inflammation, 1997
It has been suggested that the supernatant of LPSstimulated macrophages (macrophage nociceptive factor, MNF) promotes nociception in mice. Intraperitoneal administration of MNF induced dose-related writhing, which reached a plateau between 18 and 26 min ...
S. M. Thomazzi   +4 more
doaj   +1 more source

Sympatholytic Effects of Diethylaminoethanol in Man.

open access: yesExperimental Biology and Medicine, 1949
Summary and ConclusionsDoses of diethyl-aminoethanol sufficient to produce high blood concentrations resulted in a temporary inhibition of sympathetic vasoconstrictor reflexes in man. It is suggested that the effects of the drug on arterial pressure and ventricular tachycardias are secondary to its sympatholytic action.
E D, FREIS, J R, STANTON, F C, MOISTER
openaire   +2 more sources

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