Results 21 to 30 of about 1,200 (185)

Central sympatholytics prolong survival in experimental sepsis [PDF]

, 2009
Introduction One of the main causes of death in European and US intensive care units is sepsis. It involves a network of pro-inflammatory cytokines such as TNF-alpha, IL-1 beta and IL-6.
Martin, Eike, Bernhard M Graf, Stefan Hofer, Lichtenstern, Christoph, Tanja Wagner, Jochen Steppan, Markus A Weigand, Hofer, Stefan, Wagner, Tanja, Eike Martin, Funke, Benjamin, Angelika Bierhaus, Weigand, Markus A, Graf, Bernhard M, Christoph Lichtenstern, Steppan, Jochen, Benjamin Funke, Bierhaus, Angelika   +17 more
core   +1 more source

Does moxonidine reduce Achilles tendon or musculoskeletal pain in women with polycystic ovarian syndrome? A secondary analysis of a randomised controlled trial

BMC Endocrine Disorders, 2020
Background Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive and was therefore an appropriate ...
Jacob Jewson, Elisabeth Lambert, Carolina Sari, Eveline Jona, Soulmaz Shorakae, Gavin Lambert, Jamie Gaida   +6 more
doaj   +1 more source

Evaluation of Nebulised Dexmedetomidine in Blunting Haemodynamic Response to Laryngoscopy and Intubation in Adults Undergoing General Anaesthesia for Laparoscopic Surgeries: A Randomised Control Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Laryngoscopy and endotracheal intubation can trigger sympathetic stimulation, potentially leading to cardiovascular or cerebrovascular complications in high-risk patients.
Et Muhammed Jaseel, Shweta Sedani, Dipakkumar Hiralal Ruparel, Ramesh Sugandh   +3 more
doaj   +1 more source

Effect of Infusion of Dexmedetomidine on Succinylcholine-induced Fasciculation and Myalgia in ENT Surgeries: A Research Protocol [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Succinylcholine, a depolarising neuromuscular blocker, is widely used to facilitate rapid sequence intubation due to its rapid onset and short duration of action.
Kola Kavya Praneetha, Jayashree Sen
doaj   +1 more source

Pharmacotherapy of intraocular pressure: part I. Parasympathomimetic, sympathomimetic and sympatholytics

, 2009
Elevated intraocular pressure (IOP) has been recognized as the major risk factor for the development of glaucoma and a wide range of options are now available to reduce it: medical treatment, laser, filtering, or cyclodestructive surgery (alone or in ...
Parmeggiani F., dell'Omo Roberto, Parmeggiani Francesco, ROMANO, MARIO, Zeppa L, Rinaldi Michele, RINALDI, Michele, Costagliola C, Romano MR, Rinaldi M, Costagliola Ciro, dell'Omo R, PARMEGGIANI, Francesco, Zeppa Lucia   +13 more
core   +2 more sources

Direct Vasodilators and Sympatholytic Agents

Journal of Cardiovascular Pharmacology and Therapeutics, 2015
Direct vasodilators and sympatholytic agents were some of the first antihypertensive medications discovered and utilized in the past century. However, side effect profiles and the advent of newer antihypertensive drug classes have reduced the use of these agents in recent decades.
Meghan N, McComb, James Y, Chao, Tien M H, Ng   +2 more
openaire   +2 more sources

Sympatholytic Effects of Diethylaminoethanol in Man.

Experimental Biology and Medicine, 1949
Summary and ConclusionsDoses of diethyl-aminoethanol sufficient to produce high blood concentrations resulted in a temporary inhibition of sympathetic vasoconstrictor reflexes in man. It is suggested that the effects of the drug on arterial pressure and ventricular tachycardias are secondary to its sympatholytic action.
E D, FREIS, J R, STANTON, F C, MOISTER
openaire   +2 more sources

N‐terminal pro‐brain natriuretic peptide and cardiorenal outcome in patients with anaemia in chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 848-858, April 2025.
Abstract Aims Blood levels of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) may be modified by low renal clearance and anaemia. The aim of this study was to investigate the impact of the blood NT‐proBNP level on cardiovascular and renal outcomes in patients with these two manifestations.
Hiroshi Nishi, Masaomi Nangaku, Tadashi Sofue, Tatsuo Kagimura, Ichiei Narita   +4 more
wiley   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source