Dexmedetomidine: present and future directions [PDF]
Korean Journal of Anesthesiology, 2019 Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties.
Seongheon Lee
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Attenuation of Haemodynamic Parameters in Response to Pneumoperitoneum during Laparoscopic Cholecystectomy: A Randomized Controlled Trial Comparing Infusions of Propofol and Dexmedetomidine [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Effective control of sympathetic response to pneumoperitoneum is vital to avoid morbidity in patients undergoing laparoscopic surgeries. This control must be achieved without any side effects of the drugs being used as well as ensuring ...
Meyong Pincho Bhutia, Arati Rai
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Рациональная фармакотерапия в кардиологии, 2022 Refractory arterial hypertension is characterized by a lack of control of target blood pressure, despite the prolonged use >5 antihypertensive drugs with different mechanisms of action, including longacting diuretic chlorthalidone and the ...
O. B. Kuzmin, V. V. Zhezha
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Pediatric clonidine and guanfacine poisoning: a single-center retrospective review
Toxicology Communications, 2021 Clonidine and guanfacine are centrally acting sympatholytics (CAS). Poisoning with these agents is common in children, and management of this poisoning is controversial. We sought to characterize our experience with pediatric CAS poisonings.
Kevin Baumgartner, Michael Mullins
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Place of imidazoline receptor agonists in the treatment of arterial hypertension
Рациональная фармакотерапия в кардиологии, 2023 The review is devoted to one of the most controversial issues of modern antihypertensive therapy — the role of new generation sympatholytics — selective I1-imidazoline receptor agonists (AIRs).
D. V. Nebieridze +3 more
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Anesthesia and Cancer, Friend or Foe? A Narrative Review
Frontiers in Oncology, 2021 Cancer remains the leading cause of death worldwide with close to 10 million deaths reported annually. Due to growth of the advanced age cohort in our population, it is predicted that the number of new cancer cases diagnosed between now until 2035 is to ...
Julio Montejano +1 more
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BMC Endocrine Disorders, 2020 Background Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive and was therefore an appropriate ...
Jacob Jewson +6 more
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Evaluation of Nebulised Dexmedetomidine in Blunting Haemodynamic Response to Laryngoscopy and Intubation in Adults Undergoing General Anaesthesia for Laparoscopic Surgeries: A Randomised Control Trial [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Laryngoscopy and endotracheal intubation can trigger sympathetic stimulation, potentially leading to cardiovascular or cerebrovascular complications in high-risk patients.
Et Muhammed Jaseel +3 more
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Effect of Infusion of Dexmedetomidine on Succinylcholine-induced Fasciculation and Myalgia in ENT Surgeries: A Research Protocol [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Succinylcholine, a depolarising neuromuscular blocker, is widely used to facilitate rapid sequence intubation due to its rapid onset and short duration of action.
Kola Kavya Praneetha, Jayashree Sen
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