Results 31 to 40 of about 1,151 (149)

Impact of early dexmedetomidine administration on short‐ and long‐term outcomes in critically traumatic brain injury patients: A retrospective study using the MIMIC‐IV database

Ibrain, Volume 12, Issue 1, Page 137-150, Spring 2026.
Our retrospective analysis of the Medical Information Mart for Intensive Care‐IV (MIMIC‐IV) database suggests that early use of dexmedetomidine is associated with lower short‐term (28‐day and in‐hospital) and long‐term (1‐year) mortality in patients with traumatic brain injury.
Yang Long, Long‐Zhen Liu, Xiao‐Xue Tan, Yong‐Hu Zhang, Cheng‐Xi Liu, Shan Liu, Wen‐Jie Liu   +6 more
wiley   +1 more source

The effect of sex on the isolated and combined α‐ and β‐adrenergic control of blood flow during handgrip in adults at high altitude: An exploratory study

Physiological Reports, Volume 14, Issue 3, February 2026.
Abstract This study examined how sex influences blood flow during exercise at altitude and relative contributions of adrenergic mechanisms. Thirteen participants (8 M/5F) were tested at low and high altitude (days 3–11). Participants performed rhythmic handgrip for 3 min at 25% maximal voluntary contraction during local infusions of saline, propranolol
Lauren E. Maier, Emily R. Vanden Berg, Lydia Simpson, Michiel Ewalts, Katharine Foster, Jared Baylis, Christopher Gasho, David Macleod, Sean van Diepen, James Anholm, Justin Lawley, Philip N. Ainslie, Travis D. Gibbons, Michael Stembridge, Jonathan Moore, Craig D. Steinback   +15 more
wiley   +1 more source

Effects of Dexmedetomidine on the Behavioral Outcomes in Streptozotocin‐Induced Alzheimer's Disease Rats

Brain and Behavior, Volume 16, Issue 1, January 2026.
Dexmedetomidine at 25 µg/kg effectively reverses working and spatial memory deficits in a streptozotocin (STZ)‐induced rat model of Alzheimer's disease, restoring Y‐maze alternation and Morris Water Maze performance. Higher doses show no clear benefit, highlighting Dex‐25 as a promising neuroprotective candidate.
Mina Mohasel‐Roodi, Masoumeh Nozari, Ali Shamsara, Mohsen Basiri, Vida Mirzaie, Masoumeh Baghalishahi   +5 more
wiley   +1 more source

Comparison on the Effectiveness of Intravenous Magnesium Sulphate and Intravenous Dexmedetomidine in Reducing Emergence Agitation in Adults Undergoing Otorhinolaryngology Surgery

Anesthesiology Research and Practice, Volume 2026, Issue 1, 2026.
Background Emergence agitation (EA) is a phenomenon commonly occurring in otorhinolaryngology surgery. It may increase the risk of injury and prolong recovery. Dexmedetomidine is the standard preventive agent, but limited due to its high cost, limited accessibility, extubation time, and incidence of bradycardia and hypotension.
Girhanif Amri Yunda, Riyadh Firdaus, Aino Nindya Auerkari, Srijoni Sengupta   +3 more
wiley   +1 more source

Single‐Shot Intrathecal Bupivacaine With Fentanyl vs. Dexmedetomidine for Labor Analgesia: A Randomized Controlled Trial

Anesthesiology Research and Practice, Volume 2026, Issue 1, 2026.
Background Labor pain is one of the most intense physiological pains experienced by women. Single‐shot spinal analgesia (SSSA) offers rapid and reliable labor pain relief. Combining bupivacaine with adjuvants like fentanyl or dexmedetomidine has been proposed to enhance analgesic efficacy and maternal comfort.
Ayman Mohamady Eldemrdash, Taha Tairy Dardeer Elsawy, Zaher Zaki Zaher, Jehan Sadek Younan, Ahmed Mohammed Reda Ragheb, Srijoni Sengupta   +5 more
wiley   +1 more source

Chronically elevated sympathetic nervous system tone: A significant, common, and poorly realised contributor to cardiometabolic disease in type 2 diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 1595-1598, March 2026.
Ralph A. DeFronzo
wiley   +1 more source

Central sympatholytic drugs.

Journal of clinical hypertension (Greenwich, Conn.), 2012
•  Central sympatholytic drugs reduce blood pressure mainly by stimulating central α(2) -adrenergic receptors in the brainstem centers, thereby reducing sympathetic nerve activity and neuronal release of norepinephrine to the heart and peripheral circulation.
Wanpen, Vongpatanasin, Kazuomi, Kario, Steven A, Atlas, Ronald G, Victor   +3 more
openaire   +1 more source

sympatholytic

Citation: 'sympatholytic' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.16120 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Outcomes Following Radiofrequency Renal Denervation According to Antihypertensive Medications: Subgroup Analysis of the Global SYMPLICITY Registry DEFINE. [PDF]

Hypertension, 2023
Mahfoud F, Mancia G, Schmieder RE, Ruilope L, Narkiewicz K, Schlaich M, Williams B, Ribichini F, Weil J, Almerri K, Sharif F, Lauder L, Wanten M, Fahy M, Böhm M.   +14 more
europepmc   +1 more source

Central Sympatholytic Drugs [PDF]

The Journal of Clinical Hypertension, 2011
Wanpen Vongpatanasin, Kazuomi Kario, Steven A. Atlas, Ronald G. Victor   +3 more
openaire   +1 more source