Results 71 to 80 of about 8,373 (339)

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source

Pharmacological and neurophysiological aspects of space/motion sickness [PDF]

A motorized motion testing device modeled after a Ferris wheel was constructed to perform motion sickness tests on cats. Details of the testing are presented, and some of the topics covered include the following: xylazine-induced emesis; analysis of the ...
Crampton, George H., Lucot, James B.
core   +1 more source

How Does Science Come to Speak in the Courts? Citations Intertexts, Expert Witnesses, Consequential Facts, and Reasoning [PDF]

, 2009
Citations, in their highly conventionalized forms, visibly indicate each texts explicit use of the prior literature that embodies the knowledge and contentions of its field.
Bazerman, Charles
core   +1 more source

Are there valid proxy measures of clinical behaviour? [PDF]

, 2009
Background: Accurate measures of health professionals' clinical practice are critically important to guide health policy decisions, as well as for professional self-evaluation and for research-based investigation of clinical practice and process of care.
A Wilson, B Gerbert, B Gerbert, C O'Boyle, Department of Health, DL Streiner, Eileen FS Kaner, Fiona Beyer, G Hripcsak, GG Page, Heather O Dickinson, J Buellens, J Luck, J Ward, Jill J Francis, JJ Rethans, JJ Rethans, JW Peabody, JW Peabody, KC Stange, KS Chia, L Pbert, Marie Johnston, Martin P Eccles, MP Eccles, SA Flocke, Susan Hrisos, T Spies, TR Dresselhaus, TV Jones, ZE Zuckerman   +30 more
core   +3 more sources

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

A preliminary study identifying prescription factors associated with readmission [PDF]

The LACE index (1) is used by Calderdale and Huddersfield NHS Foundation Trust to refer patients to a Virtual Ward, providing post discharge support with a view to preventing readmissions. Derivation of the LACE index found the Charlson comorbidity index
Culshaw, Margaret, Culshaw, Michael, Stephenson, John, Upton, Sarah   +3 more
core  

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, EarlyView.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source

Possibilities of pharmacological correction of the artifical bladder contractile activity in experimental conditions in vivo.

Medičnì Perspektivi, 2019
The aim of this work was to study the possibility of pharmacological correction of the neobladder contractile activity of mini-pigs under the influence of new chemical compounds, m-anticholinergic (solifenacin), selective beta-2 sympathomimetic (ginipral
R. V. Savchuk, F. I. Kostyev, N. V. Shmatkova   +2 more
doaj   +1 more source

Molecular Profiling of Genes Associated With Methylphenidate Pathway Therapy and Discovery of New Variants in Amazonian Amerindian Populations

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In Attention Deficit Hyperactivity Disorder (ADHD), methylphenidate is one of the most widely used drugs, in which patient response significantly impacts prognosis. This study aimed to characterize the molecular profile of 10 genes associated with methylphenidate therapy.
Aline Pasquini Santos, Tatiane Carinta de Souza, Kaio Evandro Cardoso Aguiar, Ana Caroline Alves da Costa, Natasha Monte, Juliana Carla Gomes Rodrigues, Giovanna Gilioli da Costa Nunes, Rita de Cássia Calderaro Coelho, Ândrea Ribeiro‐dos‐Santos, André Maurício Ribeiro dos Santos, Sandro José de Souza, Sidney Emanuel Batista dos Santos, Rommel Mario Rodriguez Burbano, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos   +14 more
wiley   +1 more source

Delayed-onset drug-induced movement disorders

Psychiatry and Clinical Psychopharmacology, 2021
Delayed-onset drug-induced movement disorders (tardive syndromes) remain an important clinical problem. There are several phenomenologically and pharmacologically distinct types of tardive syndromes. The term tardive dyskinesia has been used to refer to
Oya Öztürk, Erhan Kurt, Timuçin Oral
doaj