Results 81 to 90 of about 4,147 (297)

Non‐Invasive Assessment of Perineural Invasion Density: A Novel Marker for Prognosis and Treatment Stratification in Prostate Cancer

Advanced Science, EarlyView.
This study establishes perineural invasion density (PNID) as a superior prognostic marker in prostate cancer, outperforming conventional perineural invasion in predicting biochemical recurrence and radiographic progression. Concurrent β–blocker use is associated with favorable outcomes exclusively in High–PNID patients. An MRI–based deep learning model
Bohao Liu, Long Zhang, Weian Zhu, Meng Yang, Xiang Liu, Xiaoyang Li, Peng Qin, Zhengxu Lin, Qian Cai, Jiayu Zheng, Xiao Zhao, Chen Zou, Xuan Wen, Longhao Xu, Daqin Wu, Lin Zhang, Cuilian Zhang, Kaiwen Li, Chunhui Wang, Wenlong Zhong, Yun Luo   +20 more
wiley   +1 more source

Pediatrician’s cough and cold medication prescription for hypothetical cases – A cross-sectional multi-centric study

Saudi Pharmaceutical Journal, 2016
Background: Concerns over inappropriate use of cough and cold medication (CCM) in children have been raised. In addition to being ineffective, these are now considered toxic for young children.
Sudha Chandelia, Mukesh Dhankar, Meetu Salhan   +2 more
doaj   +1 more source

Auto-modulation of release of pharmacological mediators of immediate (type I) hypersensitivity. A review

LR: 20041117; PUBM: Print; JID: 0213341; 0 (Autacoids); 0 (Kinins); 0 (Parasympathomimetics); 0 (Prostaglandins); 0 (SRS-A); 0 (Sympathomimetics); 50-67-9 (Serotonin); 51-61-6 (Dopamine); RF: 92; ppublishSource type: Electronic ...

core   +1 more source

Propofol Modulates Fear Memory Reconsolidation by Inhibiting D2 Receptor‐Expressing Neurons in the Medial Prefrontal Cortex

Advanced Science, EarlyView.
This study shows that propofol modulates fear‐memory reconsolidation in mice. It works by suppressing D2 receptor‐expressing neurons within the medial prefrontal cortex and their connections to the basolateral amygdala. D2‐receptor agonists reproduce this fear‐reducing effect, offering potential non‐anesthetic therapeutic strategies for trauma‐related ...
Jie Li, Yi‐Ge Guo, Xing Xu, Gui‐Lin Meng, Han Li, Liu‐Wei Chu, Xin‐Yuan Chen, Xiao‐Yun Guo, Tao Xu, Ti‐Fei Yuan, Ji Hu, Xiao‐Na Zhu   +11 more
wiley   +1 more source

Primary care respiratory syncytial virus disease characteristics in infants and young children in Germany: data from the prospective pediatric airway pathogen incidence surveillance network, 2021-2023

International Journal of Infectious Diseases
Objectives: Respiratory syncytial virus (RSV) is a major cause of morbidity globally, with most cases managed in outpatient settings. However, data characterizing the disease burden of non-severe RSV infections remain limited.
Alexander Kiefer, David Twardella, Jessica Bähre, Clemens Behrens, Thomas Buck, Frank Eberhardt, Mathieu Bangert, Rolf Kramer, Andrea Gerber, Martin Rosewich, Franziska Schaaff, Jan-Helge Höpner, Marcus Panning, Michael Kabesch, Christine Happle, Martin Wetzke   +15 more
doaj   +1 more source

The Efficiency of Epidural Anesthesia and Postoperative Analgesia during Myocardial Revascularization without Extracorporeal Circulation

Общая реаниматология, 2010
Objective: to evaluate the efficiency of high thoracic epidural anesthesia (EA) and analgesia during aortocoronary bypass surgery (ACBS) without extracorporeal circulation (EC). Subjects and methods.
A. V. Yeremeyev, A. A. Smetkin, M. Yu. Kirov   +2 more
doaj   +1 more source

Single‐Nucleus RNA Sequencing Identifies CREM as a Brake on Myofiber Hypertrophy in Chickens

Advanced Science, EarlyView.
Single‐nucleus RNA sequencing on 91 144 nuclei from postnatal chicken pectoralis major between fast‐growing broilers (FG) and slow‐growing layers (SG) identifies the transcriptional factor CREM as a novel brake of myofiber hypertrophy. Mechanistically, functional validation experiments confirm that CREM activates the promoter of JUN and CREM deletion ...
Shuang Gu, Xiyu Zhao, Zheyi Jiang, Chaoliang Wen, Chaoyi Wang, Qiulian Wang, Qiang Huang, Fangren Lan, Shenghui Wu, Junying Li, Congjiao Sun, Huadong Yin, Ning Yang   +12 more
wiley   +1 more source

Explosive injury. Anesthesia

Медицина неотложных состояний
Background. The combat operations taking place in Ukraine present many questions to anesthesiologists regarding the medical assistance to the injured with blast injury. Explosive trauma is combined in pathogenesis and localization.
S.M. Grytsenko, V.P. Gavrylyuk, B.A. Brik   +2 more
doaj   +1 more source

Responses to sympathomimetics in rat sensory neurones after nerve transection

, 2003
Noradrenaline activation of sensory somata that project in damaged peripheral nerves has been postulated to underlie sympathetically-mediated pain. Intracellular recordings from some neurones with myelinated axons in acutely isolated rat dorsal root ...
Lopez Armentia (20011815), A Leeson (20011818), L Urban (13436745), E McLachlan (20011821), Martin Stebbing (19228645)   +4 more
core  

Sounding Response of the Kokanee and Sockeye Salmon

, 1968
When frightened, sockeye and kokanee salmon dive into deeper waters. This is termed the "sounding response."The sounding response in these fish is accompanied by the expulsion of gas from the swimbladder via the pneumatic duct.
H. H. Harvey, W. S. Hoar, C. R. Bothern
core   +1 more source