Results 91 to 100 of about 15,584 (224)

Comparison of and as Reporter Genes for Noninvasive Imaging of Bone Mesenchymal Stem Cells Transplanted into Infarcted Rat Myocardium

open access: yesMolecular Imaging, 2011
The purpose of this study was to investigate and compare the feasibility of rat sodium iodide symporter ( rNIS ) and human sodium iodide symporter ( hNIS ) as reporter genes for noninvasive monitoring of rat bone marrow mesenchymal stem cells (rBMSCs ...
Shuo Hu   +9 more
doaj   +1 more source

TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells.

open access: yesPLoS ONE, 2020
The sodium-iodide symporter (NIS) mediates transport of iodide across the basolateral membrane of thyroid cells. NIS expression in thyroid cancer (TC) cells allows the use of radioactive iodine (RAI) as a diagnostic and therapeutic tool, being RAI ...
Márcia Faria   +5 more
doaj   +1 more source

MAPK Inhibitors Enhance HDAC Inhibitor-Induced Redifferentiation in Papillary Thyroid Cancer Cells Harboring BRAFV600E: An In Vitro Study

open access: yesMolecular Therapy: Oncolytics, 2019
Clinical efficacy of redifferentiation therapy with histone deacetylase inhibitor (HDACi) for lethal radioiodine-refractory papillary thyroid cancer (RR-PTC) is urgently needed to be improved.
Hao Fu   +5 more
doaj  

Real-time imaging of myoblast transplantation using the human sodium iodide symporter

open access: yesBioTechniques, 2005
The quantification of the graft success is a key element to evaluate the efficiency of cellular therapies for several pathologies such as Duchenne muscular dystrophy. This study describes an approach to evaluate the success of myoblast transplantation (i.
Manaf Bouchentouf   +5 more
doaj   +1 more source

Preemptive iodide treatment in the event of a nuclear disaster: The prepper's guide to the galaxy

open access: yes
Experimental Physiology, EarlyView.
Per Karkov Cramon   +2 more
wiley   +1 more source

Substrate Specificity of the H+-Sucrose Symporter on the Plasma Membrane of Sugar Beets (Beta vulgaris L.) [PDF]

open access: bronze, 1992
Roland Hecht   +4 more
openalex   +1 more source

A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression

open access: yesMolecular Therapy: Oncolytics, 2019
Colon cancer has a high rate of recurrence even with good response to modern therapies. Novel curative adjuncts are needed. Oncolytic viral therapy has shown preclinical promise against colon cancer but lacks robust efficacy in clinical trials and raises
Susanne G. Warner   +8 more
doaj  

Structural insights into the elevator-like mechanism of the sodium/citrate symporter CitS

open access: yesScientific Reports, 2017
The sodium-dependent citrate transporter of Klebsiella pneumoniae (KpCitS) belongs to the 2-hydroxycarboxylate transporter (2-HCT) family and allows the cell to use citrate as sole carbon and energy source in anaerobic conditions. Here we present crystal
Ji Won Kim   +5 more
doaj   +1 more source

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