Results 31 to 40 of about 34,958 (256)

Seaweed and Iodine Intakes and rs77277498 in Relation to Thyroid Cancer [PDF]

Endocrinology and Metabolism, 2022
Background This study aims to elucidate the associations among dietary seaweed (gim and miyeok/dashima) and iodine intakes, the rs77277498 polymorphism of the SLC5A5 gene codifying the sodium/iodine symporter, and thyroid cancer risk in a Korean ...
Tung Hoang, Eun Kyung Lee, Jeonghee Lee, Yul Hwangbo, Jeongseon Kim   +4 more
doaj   +1 more source

Functional characterization of human thyroid tissue with immunohistochemistry [PDF]

, 2007
Immunohistochemistry provides insights in the expression of functional proteins and of their localization in normal thyroid tissue and in thyroid diseases.
Bernard, Caillou, Faggiano, Antongiulio, Filetti, Sebastiano, Jean Michel Bidart,, Ludovic, Lacroix, Martin, Schlumberger, Monique, Talbot   +6 more
core   +1 more source

A symporter’s secrets shown [PDF]

Journal of General Physiology, 2017
New JGP study explores the thermodynamic cycle and cation preference of the sugar symporter MelB.
openaire   +2 more sources

Fluoride Exposure Induces Inhibition of Sodium/Iodide Symporter (NIS) Contributing to Impaired Iodine Absorption and Iodine Deficiency: Molecular Mechanisms of Inhibition and Implications for Public Health

International Journal of Environmental Research and Public Health, 2019
The sodium iodide symporter (NIS) is the plasma membrane glycoprotein that mediates active iodide transport in the thyroid and other tissues, such as the salivary, gastric mucosa, rectal mucosa, bronchial mucosa, placenta and mammary glands.
Declan T Waugh
semanticscholar   +1 more source

Goiter frequency is more strongly associated with gastric adenocarcinoma than urine iodine level [PDF]

, 2013
Purpose: We designed our study to evaluate the hypothesis that gastric cancer is correlated with iodine deficiency or thyroid dysfunction. Materials and Methods: We investigated the total body iodine reserve, thyroid function status and autoimmune ...
Adabi, K., Haghpanah, V., Hatami, E., Heshmat, R., Jahangirrad, A., Keshtkar, A., Kia, A., Larijani, B., Nabizadeh, R., Rohani, D., Roshandel, G., Semnani, S., Tabaeizadeh, M.   +12 more
core   +1 more source

Enhancement of 211At Uptake via the Sodium Iodide Symporter by the Addition of Ascorbic Acid in Targeted α-Therapy of Thyroid Cancer

Journal of Nuclear Medicine, 2019
211At is an α-emitter that has similar chemical properties to iodine and is used in targeted α-therapy. In the present study, we added ascorbic acid (AA) to 211At solution to increase the radiochemical purity of astatide and evaluated its efficacy ...
T. Watabe, K. Kaneda-Nakashima, Yuwei Liu, Y. Shirakami, K. Ooe, A. Toyoshima, E. Shimosegawa, M. Fukuda, A. Shinohara, J. Hatazawa   +9 more
semanticscholar   +1 more source

RpuS/R Is a Novel Two-Component Signal Transduction System That Regulates the Expression of the Pyruvate Symporter MctP in Sinorhizobium fredii NGR234

Frontiers in Microbiology, 2022
The SLC5/STAC histidine kinases comprise a recently identified family of sensor proteins in two-component signal transduction systems (TCSTS), in which the signaling domain is fused to an SLC5 solute symporter domain through a STAC domain.
Ana Laura Ramos, Maria Aquino, Gema García, Miriam Gaspar, Cristina de la Cruz, Anaid Saavedra-Flores, Susana Brom, Ramón Cervantes-Rivera, Ramón Cervantes-Rivera, Ramón Cervantes-Rivera, Clara Elizabeth Galindo-Sánchez, Rufina Hernandez, Andrea Puhar, Andrea Puhar, Andrea Puhar, Andrei N. Lupas, Edgardo Sepulveda   +16 more
doaj   +1 more source

Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy. [PDF]

, 2016
Treating breast cancer brain metastases (BCBMs) is challenging. Na+/I- symporter (NIS) expression in BCBMs would permit their selective targeting with radioiodide (131I-).
Ahmad, Ahn, Carlson, Carrasco, Carrasco, Carrasco, Carrasco, Carrasco, Clarke, Desai, Dirbas, Dominguez, Gambhir, Gonzalez-Angulo, Grollman, Harrington, Haveman, Ikeda, Jhiang, Jhiang, Jhiang, Kalkanis, Kang, Kirova, Lawrence, Lawrence, Lind, Link, Liu, Lorusso, Mier, Morris, Neuwelt, Nishimura, Russell, Schlumberger, Seidman, Smith, Spitzweg, Steeg, Studebaker, Vermorken, Vermorken, Wapnir, Wapnir, Wapnir, Wapnir   +46 more
core   +1 more source

Phase I Trial of Systemic Administration of Edmonston Strain of Measles Virus, Genetically Engineered to Express the Sodium Iodide Symporter in Patients with Recurrent or Refractory Multiple Myeloma

Leukemia, 2017
MV-NIS is an Edmonston lineage oncolytic measles virus expressing the human sodium iodide symporter—a means for monitoring by non-invasive imaging of radioiodine.
A. Dispenzieri, Caili Tong, B. Laplant, M. Lacy, K. Laumann, D. Dingli, Yumei Zhou, M. Federspiel, M. Gertz, S. Hayman, F. Buadi, M. O’Connor, V. Lowe, K. Peng, S. Russell   +14 more
semanticscholar   +1 more source

An efficient strategy for small-scale screening and production of archaeal membrane transport proteins in Escherichia coli.

PLoS ONE, 2013
BackgroundMembrane proteins play a key role in many fundamental cellular processes such as transport of nutrients, sensing of environmental signals and energy transduction, and account for over 50% of all known drug targets.
Pikyee Ma, Filipa Varela, Malgorzata Magoch, Ana Rita Silva, Ana Lúcia Rosário, José Brito, Tânia Filipa Oliveira, Przemyslaw Nogly, Miguel Pessanha, Meike Stelter, Arnulf Kletzin, Peter J F Henderson, Margarida Archer   +12 more
doaj   +1 more source