A chemiosmotic mechanism of symport [PDF]
Proceedings of the National Academy of Sciences, 2015 Lactose permease (LacY), a paradigm for the largest family of membrane transport proteins, catalyzes the coupled translocation of a galactoside and an H + across the Escherichia coli membrane (galactoside/H + symport).
openaire +4 more sources
Mobile barrier mechanisms for Na+-coupled symport in an MFS sugar transporter
eLifeWhile many 3D structures of cation-coupled transporters have been determined, the mechanistic details governing the obligatory coupling and functional regulations still remain elusive.
Parameswaran Hariharan +13 more
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ENDOCRINE TUMOURS: Imaging in the follow up of differentiated thyroid cancer: current evidence and future perspectives for a risk-adapted approach [PDF]
, 2016 The clinical and epidemiological profiles of differentiated thyroid cancers (DTCs) have changed in the last three decades. Today's DTCs are more likely to be small, localized, asymptomatic papillary forms.
Deandreis, Désirée +3 more
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Radioactive Iodine-Refractory Differentiated Thyroid Cancer and Redifferentiation Therapy [PDF]
Endocrinology and Metabolism, 2019 The retained functionality of the sodium iodide symporter (NIS) expressed in differentiated thyroid cancer (DTC) cells allows the further utilization of post-surgical radioactive iodine (RAI) therapy, which is an effective treatment for reducing the risk
Jierui Liu +3 more
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Measles virus causes immunogenic cell death in human melanoma [PDF]
, 2011 Oncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Bond, Jacquelyn +14 more
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[18F]Tetrafluoroborate ([18F]TFB) and its analogs for PET imaging of the sodium/iodide symporter
Theranostics, 2018 Sodium/iodide symporter (NIS)-mediated iodide uptake in thyroid follicular cells is the basis of clinical utilization of radioiodines. The cloning of the NIS gene enabled applications of NIS as a reporter gene in both preclinical and translational ...
Huailei Jiang, T. DeGrado
semanticscholar +1 more source
Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells
Nature Communications, 2018 Adoptive transfer of chimeric antigen receptor (CAR) T cells has shown promising anticancer results in clinical trials. Here the authors use the human sodium iodide symporter (hNIS) as a reporter gene to image human CAR T cells in cancer-bearing mice ...
Nia Emami-Shahri +7 more
doaj +1 more source
Carbon partitioning and export in transgenic Arabidopsis thaliana with altered capacity for sucrose synthesis grown at low temperature: a role for metabolite transporters [PDF]
, 2006 We investigated the role of metabolite transporters in cold acclimation by comparing the responses of wild-type (WT) Arabidopsis thaliana (Heynh.) with that of transgenic plants over-expressing sucrose-phosphate synthase (SPSox) or with that of antisense
Boyer J.S. +20 more
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About P systems with symport/antiport [PDF]
Soft Computing, 2004 It is proved that four membranes su±ce to P systems with minimal symport/antiport to generate all recursively enumerable sets of numbers. It is also proved that P systems with symport/antiport without maximal par- allelism are equivalent to partially blind counter automata.
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Molecular Microbiology, 2018 In response to low levels of magnesium (Mg2+), the PhoQP two component system induces the transcription of two convergent genes, one encoding a 31‐amino acid protein denoted MgtS and the second encoding a small, regulatory RNA (sRNA) denoted MgrR ...
Xuefeng Yin +5 more
semanticscholar +1 more source