Results 61 to 70 of about 15,584 (224)
Use of progress curves to estimate the co-substrate-to-substrate flow ratio of a symport mechanism. Application to the isoleucine-Na+ symport of mouse ascites-tumour cells and to the lactose-proton symport [PDF]
Biochemical Journal, 1988 The model envisages two components in the process, whereby Ht equivalents of co-substrate and St equivalents of substrate accumulate in the cellular compartment in time t. The first is the flow through the symport, n equivalents of co-substrate entering or leaving with each substrate equivalent.
E.R. Johnson, P Hopkins, A A Eddy
openaire +3 more sources
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source
Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh
eLife, 2018 Many secondary active membrane transporters pump substrates against concentration gradients by coupling their uptake to symport of sodium ions. Symport requires the substrate and ions to be always transported together.
SeCheol Oh, Olga Boudker
doaj +1 more source
Conformational Space and Dynamics of Sodium-Coupled Symporters [PDF]
Biophysical Journal, 2011 Secondary transporters utilize the free energy stored in the sodium gradient to move a solute against a concentration gradient. The transport process involves a sequence of conformational changes that exposes the substrate and ion binding sites alternatively to the extracellular and the intracellular compartment.
Beckstein, O, Sansom, M
openaire +3 more sources
Sodium-Sulfate Symport by Aplysia californica Gut [PDF]
Zoological Science, 2000 Sulfate transport across plasma membranes has been described in a wide variety of organisms and cell types including gastrointestinal epithelia. Sulfate transport can be coupled to proton, sodium symport or antiport processes involving chloride or bicarbonate. It had previously been observed in Aplysia gut that sulfate was actively absorbed.
George A. Gerencser, Randy Levin
openaire +4 more sources
ChemistryOpen, EarlyView.A method to detect perchlorate ions and certify safe drinking water by constructing a fluorescence‐based logic gate considering the binding of a hemicyanine dye with β‐CD is presented. Perchlorate ions (ClO4−) are prevalent contaminants in the surface, and drinking water that disrupt thyroid function by competitively inhibiting the sodium‐iodide ...
Anusha C. M. +4 more
wiley +1 more source
Genome Analysis of a New Rhodothermaceae Strain Isolated from a Hot Spring
Frontiers in Microbiology, 2016 A bacterial strain, designated RA, was isolated from water sample of a hot spring on Langkawi Island of Malaysia using marine agar. Strain RA is an aerophilic and thermophilic microorganism that grows optimally at 50–60°C and is capable of growing in ...
Kian Mau Goh +7 more
doaj +1 more source
A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters [PDF]
Nature Structural & Molecular Biology, 2014 Neurotransmitter/sodium symporters (NSSs) terminate synaptic signal transmission by Na+-dependent reuptake of released neurotransmitters. Key conformational states have been reported for the bacterial homolog LeuT and an inhibitor-bound Drosophila dopamine transporter. However, a coherent mechanism of Na+-driven transport has not been described.
Lina Malinauskaite +6 more
openaire +4 more sources
N‐acetylglucosamine sensing in the filamentous soil fungus Trichoderma reesei
The FEBS Journal, EarlyView.N‐acetylglucosamine (GlcNAc) is involved in diverse signaling pathways in dimorphic yeasts and bacteria, including virulence and cell death. Here, we investigated GlcNAc sensing in Trichoderma reesei. GlcNAc signaling influences around 2100 genes in this filamentous soil fungus.
Sadia Fida Ullah +6 more
wiley +1 more source
The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles
Insect Molecular Biology, EarlyView.Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork +3 more
wiley +1 more source