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The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum. [PDF]
Karapanagioti F+3 more
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Current Drug Targets - Immune, Endocrine & Metabolic Disorders, 2004
The sodium-iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active transport of iodide in the thyroid gland and several other extra-thyroidal tissues. This activity has been utilized for many years for imaging the thyroid gland and for treatment of thyroid disease both benign and malignant.
Claire H. Baker, John C. Morris
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The sodium-iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active transport of iodide in the thyroid gland and several other extra-thyroidal tissues. This activity has been utilized for many years for imaging the thyroid gland and for treatment of thyroid disease both benign and malignant.
Claire H. Baker, John C. Morris
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Sodium/iodide symporter in thyroid cancer
Experimental and Clinical Endocrinology & Diabetes, 2001[No abstract available]
C. Mian+5 more
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Thyroid hormone stimulates the Na(+)-PO4 symporter but not the Na(+)-SO4 symporter in renal brush border [PDF]
In our previous studies we established that thyroid hormones [L-thyroxine (T4) or 3,5,3'-triiodothyronine (T3)] elicit an increase in Na(+)-Pi symport in rat and mouse renal brush-border membrane (BBM) vesicles (BBMV), but the Na(+)-coupled symports of other solutes were not influenced. However, a recent report [H. S. Tenenhouse, J. Lee, and N. Harvey.
K. W. Beers, Thomas P. Dousa
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Sodium Iodide Symporter in Health and Disease
Thyroid, 2001Radioiodine-concentrating activity in thyroid tissues has allowed the use of radioiodine as a diagnostic and therapeutic agent for patients with thyroid disorders such as well-differentiated thyroid cancer. However, some extrathyroidal tissues also take up radioiodine, contributing to unwanted side effects of radioiodine therapy.
Richard T. Kloos+3 more
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A functional superfamily of sodium/solute symporters
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1994Eleven families of sodium/solute symporters are defined based on their degrees of sequence similarities, and the protein members of these families are characterized in terms of their solute and cation specificities, their sizes, their topological features, their evolutionary relationships, and their relative degrees and regions of sequence conservation.
Milton H. Saier+2 more
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Uniporters, Symporters and Antiporters
Journal of Experimental Biology, 1994ABSTRACT Transporters are a diverse group of membrane proteins that facilitate the movement of water-soluble solutes through the lipid bilayer of biological membranes. The least complex transporters are the uniporters (Kakuda and MacLeod, 1994).
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