Results 241 to 250 of about 12,546 (277)
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Sodium/iodide symporter in thyroid cancer
Experimental and Clinical Endocrinology & Diabetes, 2001[No abstract available]
C. Mian+5 more
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Thyroid hormone stimulates the Na(+)-PO4 symporter but not the Na(+)-SO4 symporter in renal brush border [PDF]
In our previous studies we established that thyroid hormones [L-thyroxine (T4) or 3,5,3'-triiodothyronine (T3)] elicit an increase in Na(+)-Pi symport in rat and mouse renal brush-border membrane (BBM) vesicles (BBMV), but the Na(+)-coupled symports of other solutes were not influenced. However, a recent report [H. S. Tenenhouse, J. Lee, and N. Harvey.
K. W. Beers, Thomas P. Dousa
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Sodium Iodide Symporter in Health and Disease
Thyroid, 2001Radioiodine-concentrating activity in thyroid tissues has allowed the use of radioiodine as a diagnostic and therapeutic agent for patients with thyroid disorders such as well-differentiated thyroid cancer. However, some extrathyroidal tissues also take up radioiodine, contributing to unwanted side effects of radioiodine therapy.
Richard T. Kloos+3 more
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Cloning of the Human Sodium Iodide Symporter
Biochemical and Biophysical Research Communications, 1996The iodide concentrating activity of the thyroid gland is essential to the production of thyroid hormone and also provides a mechanism for the treatment of thyroid cancer by radioiodine ablation. We report here the nucleotide and amino acid sequence of the human sodium iodide symporter (hNIS), which mediates the iodide uptake activity in the thyroid ...
Patricia A. Smanik+6 more
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Photosynthesis Research, 1992
The heterotrophic tissues of the plant are dependent upon carbon and nitrogen import for normal growth and development. In general, oxidized forms of these essential elements are reductively assimilated in the leaf and, subsequently, sucrose and amino acids are transported to the heterotrophic cells in a process known as assimilate partitioning.
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The heterotrophic tissues of the plant are dependent upon carbon and nitrogen import for normal growth and development. In general, oxidized forms of these essential elements are reductively assimilated in the leaf and, subsequently, sucrose and amino acids are transported to the heterotrophic cells in a process known as assimilate partitioning.
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A functional superfamily of sodium/solute symporters
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1994Eleven families of sodium/solute symporters are defined based on their degrees of sequence similarities, and the protein members of these families are characterized in terms of their solute and cation specificities, their sizes, their topological features, their evolutionary relationships, and their relative degrees and regions of sequence conservation.
Milton H. Saier+2 more
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Uniporters, Symporters and Antiporters
Journal of Experimental Biology, 1994ABSTRACT Transporters are a diverse group of membrane proteins that facilitate the movement of water-soluble solutes through the lipid bilayer of biological membranes. The least complex transporters are the uniporters (Kakuda and MacLeod, 1994).
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Inhibitors of the Proton-Sucrose Symport
Archives of Biochemistry and Biophysics, 1993Sucrose transporters are important components of the assimilate partitioning pathway in many plants. In the results reported here, we examined the effect of several inhibitors on proton-coupled sucrose transport into plasma membrane vesicles isolated from sugar beet leaf tissue.
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Cloning of the Mouse Sodium Iodide Symporter
Thyroid, 2001The iodide-concentrating ability of the thyroid gland is essential to the production of thyroid hormone. We report the nucleotide and amino acid sequence of the mouse sodium iodide symporter (mNIS), which mediates this activity within the thyroid gland.
Charyl M. Dutton+5 more
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The chlorella hexose/H+-symporters
2000The physiology, molecular biology, and biochemistry of the inducible hexose uptake protein of Chlorella kessleri is reviewed. The protein encoded by the HUP1 gene is the most intensively studied membrane transporter of plants. Responsible for substrate accumulation up to 1500-fold, it translocates one proton together with one hexose, and the cell ...
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